There are about two kinds of prescriptions of the same name for Shenxian Huoxue Yin, among which Shenfang Huoxue Yin, which is recorded in Volume 24 of Notes for Girls' Schools, is the most commonly used prescription. It consists of 6 grams of pangolin scales (fried), 6 grams of radix Saposhnikoviae, 6 grams of myrrh, 6 grams of Radix Paeoniae Rubra, 3 grams of Radix Angelicae Dahuricae, 6 grams of angelica tail, 6 grams of frankincense, 6 grams of Fritillaria, 6 grams of Trichosanthes root, 6 grams of Gleditsia sinensis, 9 grams of honeysuckle, 9 grams of dried tangerine peel and 6 grams of licorice. This prescription has the effects of clearing away heat and toxic materials, reducing swelling and resolving hard mass, promoting blood circulation and relieving pain, and is mainly used for treating carbuncle at the beginning. Symptoms include carbuncle swelling, local swelling and pain, slight body heat and aversion to cold, thin white or yellow tongue coating and strong pulse. This prescription is the representative prescription for treating carbuncle swelling and toxin at the beginning. It is often used to treat suppurative inflammation of soft tissue infection, such as carbuncle, cellulitis, mastitis, furuncle, impetigo, deep abscess and so on.
Shenxian Huosheng Decoction (Volume 20) in Fuzhengliangfang is mainly used for suppurative infection, with broad antibacterial spectrum and strong efficacy, especially most drugs are aimed at common pathogenic bacteria such as Staphylococcus aureus and hemolytic streptococcus; At the same time, the prescription has strong anti-inflammatory, antipyretic and analgesic effects; Some drugs can improve microcirculation and play the role of "promoting blood circulation and removing blood stasis" at the infected site. However, from the perspective of modern medicine, the ingredients of this prescription are complex. From the perspective of modern medicine, some drugs have not been found to have effective therapeutic effects on suppurative and infectious diseases. For severe furuncle and cellulitis, modern medical surgery and effective antibiotics should be combined. [ 1]
3. 1 Alias of immortal live drink: immortal live drink (Volume 24 of Women's Annotation) and real live drink (Volume 8 of Shousheng Zhongmiaofang).
3.2 Prescription: Chuanshanjia, Glycyrrhiza uralensis Fisch, Saposhnikovia divaricata, Myrrha, Radix Paeoniae Alba, Radix Angelicae Dahuricae, 1.8g, Ramulus Cinnamomi, Bulbus Fritillariae Cirrhosae, Trichosanthis Radix, Thorn 3g, Flos Lonicerae and Pericarpium Citri Tangerinae 9g.
Pangolin (parched) 6g, Saposhnikovia divaricata 6g, Myrrha 6g, Radix Paeoniae Rubra 6g, Radix Angelicae Dahuricae 3g, angelica tail 6g, Olibanum 6g, Bulbus Fritillariae Cirrhosae 6g, Trichosanthis Radix 6g, Gleditsia sinensis 6g, Flos Lonicerae 9g, Pericarpium Citri Reticulatae 9g and Glycyrrhrizae Radix 6g[2].
Radix Angelicae Dahuricae 6g, Fritillaria 6g, Radix Saposhnikoviae 6g, Radix Paeoniae Rubra 6g, angelica tail 6g, Radix Glycyrrhizae 6g, Fructus Gleditsiae Abnormalis 6g, Squama Manis 6g, Trichosanthis Radix 6g, Myrrha 6g, Flos Lonicerae 25g, and Pericarpium Citri Tangerinae 9g[3].
3.3 The main function is Shenxian Huosheng Drink, which has the effects of clearing away heat and toxic materials, reducing swelling and resolving hard mass, promoting blood circulation and relieving pain. Indications: sore pain, initial swelling and pain, or slight body heat and aversion to cold, thin white or yellowish tongue coating, strong pulse, which belongs to yang syndrome.
3.4 Usage and dosage of Shenxian Shenghuo Drink Use 600 ml of good wine and fry it to 300 ml. If the upper body is taken after meals and the lower body is taken before meals, add 150 ~ 200ml alcohol to help. Cannot be changed.
Use a big bowl of wine and fry it five or seven times. [3]
3.5 1 application. This prescription is the representative prescription for treating carbuncle and swelling. This recipe can be used to treat carbuncle, carbuncle, sore, yang syndrome at the beginning, local redness, swelling, heat and pain, or accompanied by fever, slight aversion to cold, thin white or yellow tongue coating, strong pulse and other symptoms. In addition to decoction and oral administration, the residue can also be mashed and externally applied to the affected area. [2]
2. Addition and subtraction: if the swelling and pain are serious and the heat toxicity is serious, dandelion, viola yedoensis, forsythia, wild chrysanthemum, etc. Increases the efficacy of clearing away heat and toxic materials; For those with excessive heat and thirst, Radix Angelicae Dahuricae and Pericarpium Citri Tangerinae with pungent dryness should be reused, and Radix Scrophulariae and Radix Ophiopogonis can be added to clear away heat and promote fluid production. Constipation, increasing jaundice, purging heat and relaxing bowels; According to the different parts of sores and swelling, menstruation-dredging drugs can be added appropriately to make the drugs directly reach the disease. [2] In addition to decoction and oral administration, the residue can be mashed and applied externally. [4]
3. Note: Our ancestors called it "the holy medicine for sores, the first prescription for surgery". It is suitable for all kinds of sores, sores, swelling and toxins embodied in yang syndrome. The main points of syndrome differentiation and treatment are local swelling and pain, even accompanied by body heat and strong pulse. The pus can be eliminated if it is not discharged, and it can collapse if it is discharged. However, it should be noted that it can only be used before carbuncle swelling, but not after carbuncle collapse. Yin syndrome sores and ulcers are contraindicated; Use with caution those with deficiency of spleen and stomach and deficiency of qi and blood. [3]
3.6 Solutions [3]
At the beginning, carbuncle is swollen and painful, which belongs to yang syndrome. A kind of carbuncle with toxic swelling is mostly caused by heat toxicity, qi stagnation, blood stasis and phlegm coagulation. Symptoms are redness, swelling, fever, pain, and even accompanied by systemic symptoms. For carbuncle with yang syndrome, it must be treated by clearing away heat and toxic materials, rationally promoting qi and blood circulation, and dispersing stagnation and expelling wind. The prescription takes honeysuckle as the monarch, and its taste is sweet and cold, and it is the best for clearing heat and detoxifying. However, if it is only used for clearing away heat and toxic materials, the qi stagnation and blood stasis will not disappear and the swelling will not go away. Therefore, Angelica sinensis, Radix Paeoniae Rubra, Olibanum, Myrrha, and Orange Peel are used as ministers, which can promote the circulation of qi, dredge collaterals, promote blood circulation and remove blood stasis, reduce swelling and relieve pain, and promote the circulation of qi, which will make the camp and guard unobstructed, so as to remove blood stasis and relieve pain, while Angelica dahurica and Saposhnikovia divaricata can go deep into the camp and guard, dispel wind, relieve exterior symptoms, dissipate stagnation and relieve swelling; Squama Manis and Gleditsia sinensis pass through meridians, which can lead to abscess collapse. Pollen and Fritillaria can clear away heat, eliminate phlegm and expel pus, which can make them disappear. They are all auxiliary drugs. Licorice is used to help clear away heat and toxic materials, and to reconcile various drugs. Those who add wine to decoction can use it to remove blood stasis and clear the circulation, and help the medicine to reach the affected area directly. The combination of all the medicines has the functions of clearing away heat and toxic materials, removing blood stasis and resolving hard mass, expelling wind and reducing swelling.
This prescription belongs to the representative prescription of "fighting poison with poison" in surgery. The whole prescription tastes bitter and cold, and integrates the methods of clearing away heat and toxic materials, expelling wind and relieving exterior syndrome, removing blood stasis and resolving hard mass. Its drug compatibility embodies the compatibility characteristics of internal treatment and external treatment in surgery. This prescription and Puji Disinfection Drink are both heat-clearing and detoxicating prescriptions, but Puji Disinfection Drink is used to treat big head plague caused by swelling and toxin on the head and face. The treatment method is clearing away heat and toxic materials, expelling wind and pathogenic factors, and promoting yang to disperse fire to dissipate stagnation heat. This recipe can be used to treat yang syndrome with swelling and toxin, and it is more suitable for carbuncle at the beginning when clearing away heat and toxic materials. It is combined with herbs for activating qi and promoting blood circulation, dispersing stagnation and relieving swelling.
3.7 Modern indications [4]
Indications: Used for suppurative inflammation, such as cellulitis, suppurative tonsillitis, mastitis, impetigo, furuncle, deep abscess, etc.
3.7. 1 furuncle is a bacterial infectious purulent skin disease involving the deep hair follicle and its surrounding tissues. At first, it mainly showed local redness, heat pain and induration. After a few days, the center becomes soft and has a sense of fluctuation, and white pus thrombus appears at the top. Exhaustion of pus and necrotic tissue after shedding.
3.7.2 Pyogenic tonsillitis Hemolytic Streptococcus B is the pathogen of acute tonsillitis. Non-hemolytic Streptococcus, Staphylococcus, Streptococcus pneumoniae, Influenza Bacillus, Adenovirus, Rhinovirus and Herpes Simplex Virus can also cause this disease. When the human body's resistance is reduced, pathogens multiply, toxins destroy the crypt epithelium, and pathogens invade the tonsil parenchyma and get sick. The inflammation of virus-infected people is limited to the mucosal surface, mostly acute catarrhal tonsillitis; Acute follicular tonsillitis is inflammation invading lymphatic follicles in tonsil parenchyma, causing congestion, swelling and suppuration, which is called acute follicular tonsillitis. When the tonsils are congested and swollen, the crypt is filled with exudate and discharged from the crypt, and sometimes there is a false membrane connected together, which is called occult tonsillitis.
3.7.3 cellulitis cellulitis, mostly hemolytic streptococcus, Staphylococcus aureus, Escherichia coli or other streptococci enter the subcutaneous connective tissue through the damaged skin mucosa, which can occur in the skin, fascia, muscle space or deep cellulite. Pathogens release highly toxic hemolysin, streptokinase and hyaluronidase. , make the tissue edema and necrosis, the lesion expands rapidly, and the nearby lymph nodes can also be invaded. In general, subcutaneous cellulitis has a blurred boundary between epidermal swelling and swelling. When it continues to develop, the skin turns brown locally, and it can bubble and flow out pus after rupture. Aerogenic subcutaneous cellulitis is often mainly invaded by anaerobic bacteria, such as enterococcus, facultative Escherichia coli, Proteus, Bacteroides or Clostridium perfringens, which are confined to connective tissue and do not invade muscle layer. After bursting, the smell is unpleasant, and the general condition deteriorates rapidly.
3.7.4 Mastitis Mastitis is actually cellulitis that grows on the breast, mainly due to milk deposition, * * * rupture or chapped, so that bacteria directly invade the mammary duct, and ascending mammary lobules make this part of the tissue edema, degeneration, necrosis and abscess. The main clinical manifestations are * * * pain, local redness and fever, and in severe cases, symptoms such as fever and chills may occur.
3.7.5 pustulosis pustulosis is a purulent skin lesion spread by Staphylococcus aureus or Streptococcus hemolyticus B through close contact or self-inoculation. Bacteria mainly invade epidermis, causing suppurative inflammation; Coagulase-negative phage group ⅱ T 1 Staphylococcus aureus can produce epidermal exfoliating toxin, which causes toxemia and systemic epidermal relaxation and necrosis. People with low resistance can cause bacteremia or septicemia; A few can induce nephritis or rheumatic fever. There are three kinds of common pustulosis in clinic, deep pustulosis and bullous pustulosis. At first, it is mainly manifested as erythema, then it turns into pustule, and then it ruptures, erodes and pustules to form a thick yellow scab. In severe cases, it can peel off a large area.
3.8 Pharmacological Effects of Shenxian Huosheng Drink [5]
3.8. 1 Honeysuckle, the monarch drug against pathogenic microorganisms, has broad-spectrum antibacterial effect, especially against Staphylococcus aureus, hemolytic streptococcus, pneumococcus, meningococcus, typhoid bacillus, paratyphoid bacillus, dysentery bacillus, Pseudomonas aeruginosa, Proteus, Bordetella pertussis, Mycobacterium tuberculosis, Escherichia coli, Staphylococcus albus, Streptococcus mutans, Neisseria gonorrhoeae and cholera. It can inhibit leptospira, some dermatophytes, oral bacteria, influenza virus, herpes simplex virus, coxsackie virus, echovirus virus, orphan virus, etc. The combination of honeysuckle and penicillin can supplement and enhance the antibacterial effect. Its effective antibacterial components are chlorogenic acid and isochlorogenic acid. At the same time, honeysuckle also has the function of resisting bacterial endotoxin, which can not only remove endotoxin, but also have antipyretic effect on fever caused by it and reduce the death caused by endotoxin. Angelica sinensis has inhibitory effects on Staphylococcus aureus, Escherichia coli, Typhoid Bacillus, Dysentery Bacillus, Diphtheria Bacillus and Pseudomonas aeruginosa. The antibacterial spectrum of Radix Paeoniae Rubra is almost the same as that of Flos Lonicerae, and it has certain inhibitory effect on influenza or parainfluenza virus, herpes virus and some enteroviruses. Myrrh mainly inhibits a variety of pathogenic fungi. Angelica dahurica, an auxiliary material, has a certain inhibitory effect on Escherichia coli and fungi. Saposhnikovia divaricata has a strong inhibitory effect on staphylococcus aureus, hemolytic streptococcus and other bacteria, as well as some fungi and viruses. Gleditsia sinensis has insecticidal effect. Trichosanthes root can inhibit staphylococcus aureus, hemolytic streptococcus and HIV. Glycyrrhiza uralensis Fisch can not only inhibit some of the above bacteria, but also inhibit Helicobacter pylori, amoeba and trichomonas, and has a broad-spectrum antiviral effect, especially on herpes simplex virus, varicella-zoster virus and AIDS virus. Glycyrrhiza polysaccharide can inhibit vesicular stomatitis virus, herpes simplex virus type I and vaccinia virus. Glycyrrhizic acid has strong anti-Coxsackie virus, adenovirus and syncytial virus. Glycyrrhizin can not only inhibit the above virus, but also inhibit hepatitis virus. Monoamine glycyrrhizinate can also inhibit HIV. It can be seen that eight drugs in this prescription 13 have the function of resisting pathogenic microorganisms, and most of them have antagonistic effects on bacteria that are easy to cause tissue infection, such as Staphylococcus aureus, hemolytic streptococcus, Escherichia coli, etc., which may be the center of this prescription.
3.8.2 Anti-inflammatory, anti-oxidation, antipyretic and analgesic effects: Nine of the three herbs in this recipe/KLOC-0 have definite anti-inflammatory and antipyretic effects. Honeysuckle, the monarch drug, has obvious anti-inflammatory effect, and its effective component, Lonicera flavescens total glycoside, plays an anti-inflammatory role by exciting pituitary-adrenal axis, which has inhibitory effect on all processes of inflammation. At the same time, honeysuckle acts on the heat-sensitive neurons in the front of hypothalamus, making them return to normal level, inhibiting the release impulse of cold-sensitive neurons and reducing the heat production level of antibodies, thus playing the role of antipyretic and analgesic. Ferulic acid contained in Angelica sinensis has broad-spectrum antiallergic effect. Danggui decoction has obvious inhibitory effect on acute and chronic inflammation caused by various inflammatory factors, and can inhibit the release of PGE2 in inflammatory tissues, reduce the hemolytic activity of complement bypass, and has obvious analgesic, sedative and anticonvulsant effects. It can resist the oxidation of superoxide anion and H2O2 on red blood cells, and can scavenge free radicals to reduce malondialdehyde, the product of membrane lipid peroxidation, so it also has obvious anti-inflammatory effect. Paeoniflorin, paeoniflorin and paeonol contained in Radix Paeoniae Rubra have obvious anti-inflammatory effects, obvious inhibitory effects on various inflammatory factors and inflammatory processes, and obvious inhibitory effects on immune inflammation. Myrrh, a minister medicine, has obvious anti-inflammatory and detumescence effects, has astringent effects on mucosal injury, and has antipyretic and analgesic effects. Frankincense has obvious inhibitory effect on inflammatory exudation, edema and granulation tissue proliferation. Hesperidin and methyl hesperidin contained in dried tangerine peel have significant inhibitory effects on the increase of inflammatory capillary permeability and granuloma. Imperatorin contained in Radix Angelicae Dahuricae also has anti-inflammatory effect, and has obvious antipyretic, sedative and analgesic effects. Saposhnikovia divaricata plays an anti-inflammatory role by enhancing immune function, and has obvious antipyretic, cooling, analgesic, sedative and anticonvulsant effects. Pangolin also has anti-inflammatory effect. Gleditsia sinensis has the function of detumescence and pus seepage. Glycyrrhiza uralensis Fisch can stimulate hypothalamus-pituitary-adrenal cortex axis to produce corticosteroid-like effect, and at the same time, Glycyrrhiza uralensis Fisch can inhibit PGE2, reduce endogenous PGE2 production and play an anti-inflammatory role. Its anti-inflammatory and antipyretic effects have hydrocortisone-like effects, which can inhibit the stage I, II and III of inflammation. Glycyrrhiza uralensis Fisch also has the effects of scavenging free radicals, resisting oxidative damage, resisting allergy and inhibiting immune inflammation. At least seven drugs in this prescription have antipyretic and analgesic effects.
3.8.3 Effects on heart, circulation and hemorheology Angelica has anti-platelet aggregation and anti-thrombosis effects, can promote the formation of hemoglobin and red blood cells, has anti-myocardial ischemia, anti-arrhythmia and vasodilation effects, and its ferulic acid can improve microcirculation. Radix Paeoniae Rubra can dilate coronary artery, improve the body's hypoxia tolerance, and has the effects of anti-platelet aggregation, anti-thrombosis, anti-coagulation, activating fibrinolysis and improving microcirculation. Low dose Chenpi can enhance myocardial contractility, increase cardiac output, reduce capillary permeability, prevent microvascular bleeding, enhance fibrinolysis and prevent thrombosis. Pangolin can reduce blood viscosity and prolong coagulation time. Fritillaria can dilate blood vessels and resist platelet aggregation. The main function of wine is to dilate blood vessels and inhibit platelet aggregation. Flavonoids contained in Glycyrrhiza uralensis Fisch can narrow the scope of acute myocardial infarction and resist arrhythmia. Glycyrrhetinic acid has the agonist-like effect of angiotensin ⅱ on 1 receptor. Licorice can also inhibit platelet aggregation, inhibit thrombosis, reduce blood lipid and resist arteriosclerosis, which is the so-called "promoting blood circulation and removing blood stasis" effect of traditional Chinese medicine.
3.9 from "women's prescription proofreading" Volume 24.
4 "Additional Notes of Danxi Heart Method" Volume 16 Fairy Life Drink 4. 1 Fairy Life Drink
4.2 Flos Lonicerae 1.25 yuan, Fructus Gleditsiae Abnormalis 1.25 yuan, Bulbus Fritillariae Cirrhosae (enucleated) 4 yuan, Trichosanthes 4 yuan, angelica tail 5 yuan, Olibanum 5 yuan, Rhubarb 5 yuan, Myrrha 3 yuan, Semen Momordicae (shelled) 3 yuan, Glycyrrhrizae Radix 3 yuan, Pangolin scales (fried with clam powder, ground and washed).
4.3 Indications: Shenxian Life Drink, a prescription in Addendum to Danxi Heart Therapy (volume 16), is used to treat carbuncle, lumbago, headache, epiphyseal pain, dysmenorrhea, furuncle, abdominal distension, leg carbuncle, carbuncle with bone, malignant ulcer and so on.
4.4 Dosage of Immortal Life Drinking Method: Each dose of 5 yuan, decocted in water, taken up and down depending on the condition.
4.5 Add and subtract the elderly and the physically weak, and give birth to half of Astragalus membranaceus; Jiubao band drink is suitable for people with visceral obstruction.
4.6 Excerpts