The characters are bitter, cold and poisonous.
1 Guiyang folk herbs: hard hemp, big poison.
② Guizhou herbs: cold in nature, pungent in taste and poisonous.
Function is mainly used to treat carbuncle swelling and toxin. Scabies, boils, burns.
① "Convenient Prescription of Materia Medica": Treating wind, eye, carbuncle, swollen cheeks, wind poison and numbness of limbs.
② "classification of drugs": to treat fire injury, and apply it with sesame oil.
(3) Chongqing herbal medicine: dried leaf powder, which can collect yellow water, relieve itching and cure itching, sores and boils.
Usage and dosage for external use: pound, fry, wash, grind, mix or blend.
Scheme ① Treatment of swelling and pain ulcer: fry the fishtail leaves and wash them. (Hunan Pharmacology)
② Treatment of scabies: fishtail leaf, Saturn show, etc. Divided into powder, mixed oil and friction. (Guiyang folk herbs)
③ Treatment of pinkeye pain: fishtail leaf. Caulis Sargentodoxae leaves, mashed and smeared. (Hunan Pharmacology)
Treatment of external hemorrhoids: Take proper amount of fishtail leaves, fry them with slow fire, and wash the affected area. (Guizhou herbs)
⑤ Treatment of tinea capitis: One or two tender leaves of Coriaria sinica are tender and fluffy. Add sulfur powder, San Qian and pepper, mix with vegetable oil and rub on the affected area. The chemical and pharmacological properties of coriaria lactone, a toxic component of Guizhou Materia Medica, are similar to those of tetrandrine, and its antispasmodic effect occurs faster, lasts shorter than the latter, and is more toxic than the latter, so it is not used in clinic. It has a good antagonistic effect on barbiturates. Intravenous injection below spasticity (0. 1-0.2mg/kg) can cause the blood pressure of rabbits and cats to increase continuously. It doesn't cause spinal cat spasms or L-stress. It has no effect on the respiration of rabbit ear blood vessels, isolated rabbit atrium, isolated rabbit intestine, uterus and brain tissue.
Harvest in April-May. Treat schizophrenia
Take fresh cauliflower or stem (stem diameter 1 ~ 2.5cm, sliced), add water and decoct for two times, and then combine and concentrate into 100% decoction for oral administration. The dosage of/kloc-0 per time is about 2 ~ 4g/kg of crude drug weight (if mulberry leaves are left for too long after collection, the efficacy will be reduced, so the dosage should be increased appropriately). During the treatment, patients are concentrated in the treatment room, with special care. Take medicine on an empty stomach that morning, and then let the patient stay in bed. Generally, about 0.5 ~ 1 hour after administration, drug reactions such as nausea, vomiting, sweating, muscle twitching and general spasm may occur. After about 8 hours, the drug reaction gradually disappears and can be sent back to the ward for further observation. If seizures are frequent and the interval between seizures is shortened after administration, quick-acting antiepileptic drugs (pentobarbital sodium 0.5g or diazepam injection 10 mg, intramuscular injection) can be given. If the reaction is not serious, no special treatment is needed, but 0. 1 g phenobarbital sodium should be injected intramuscularly at the end of the treatment on the same day to prevent seizures after leaving the treatment room.
After treatment 128 cases (among which 29 cases were combined with other therapies), 33 cases were cured (the mental symptoms disappeared completely, the insight recovered, and they adapted well to the environment), and 2/kloc-0 cases were significantly improved (the main mental symptoms basically disappeared, with initial insight and good contact with the environment), and 265,438 cases were improved (the main mental symptoms were relieved and life could take care of themselves) The total effective rate is about 60%, and the cure rate is 25.8%. Among them, the curative effect of 99 cases treated with Masang Decoction alone is: cured 18 cases, markedly effective 14 cases, improved 18 cases, and ineffective in 49 cases. More than 80% of effective cases show effect within 7 days of treatment, and the fastest is only 1 ~ 2 days.
In order to observe the toxic effect of drugs, 96 patients were examined for liver function during the treatment. The results showed that 9 patients had obvious changes, but no symptoms of acute toxic hepatitis such as jaundice and liver pain were found, only a few cases had anorexia and liver enlargement. Some patients found a small amount of red blood cells, white blood cells and trace proteins in urine after routine urine examination, and returned to normal after a few days. Blood sugar and serum electrolyte were also observed in some cases, and the results showed no significant changes. In the treatment, a few cases also caused some complications due to drug reactions, such as a small amount of stomach bleeding in patients with severe vomiting, and the vomit was brown (atropine was injected subcutaneously at this time); Or epilepsy may cause dislocation of mandible and shoulder joint, compression fracture of thoracic vertebra and loosening of front teeth. In addition, 1 patient suffered from toxic shock after taking medicine (equivalent to1.25g of crude drug) and was rescued in time.
In view of the toxicity and severe reaction after taking this product, it is not suitable for anyone who has serious acute and chronic visceral diseases, weak constitution or is not suitable for treatment by this product. General patients should also do blood routine, urine routine and liver function examination before treatment, and make a chest X-ray when necessary; In order to protect the liver, give sugar and vitamins every day before and after treatment; In addition to antiepileptic drugs, we should also pay attention to protecting joints to prevent and reduce the occurrence of complications such as dislocation and fracture.
Experience has proved that in order to obtain a good therapeutic effect, the dosage should be appropriately increased or decreased according to the initial response of patients to treatment, and it is generally appropriate to control the dosage in grand mal for no more than 5 times during the treatment period. Repeated treatment is needed many times. A course of treatment can be tried 3 ~ 5 times, with an interval of 5 ~ 7 days. Practice shows that this product has a good curative effect on patients with short course of disease, but there are also a few patients with long course of disease who are ineffective after various treatments and are cured by fishtail therapy. Fistula has a certain effect on various common symptoms of schizophrenia, and it seems that there is no obvious selectivity. This method can be combined with other methods to treat schizophrenia, complement each other, improve the curative effect and consolidate the effect. Among the cured and significantly improved cases, a small number (about 30%) fluctuated before discharge, and the fishtail treatment was either effective or ineffective again; Some cases will recur after discharge. Therefore, for effective cases, chlorpromazine hydrochloride or perphenazine should be given before and after discharge to consolidate the curative effect.
It is also worth noting that pharmaceutical preparations have a great influence on clinical efficacy. For example, fresh preparations take effect quickly and have a high curative effect, while preparations that are left for too long after preparation take effect slowly and have a low curative effect; The storage time of fishtail medicinal materials has a particularly obvious effect on the curative effect, especially after mulberry leaves are collected, the efficacy is declining day by day, the efficacy of dried fishtail leaves is not great, and the situation of fishtail stems is not as obvious as that of fishtail leaves. Therefore, the dosage of the prepared decoction needs to be appropriately increased day by day to produce a reaction and obtain a curative effect.