Brief introduction of Mingmu Dihuang pill

Directory 1 Pinyin 2 English Reference 3 National Essential Drugs 4 Overview 5 Cha Yao Han Volume 5 Mingmu Dihuang Pills 5. 1 Composition 5.2 Mingmu Dihuang Pills Usage and Dosage 5.3 Efficacy and Indications 6 Buwan Rejuvenation Volume 5 Mingmu Dihuang Pills 6.6 5438+0 Prescription 6.2 Composition 6.3 Efficacy 6.4 Indications 6.5 Mingmu Dihuang Pills Usage and Dosage 6.6 Preparation Method Kloc-0/ Mingmu Dihuang Pill 77.4 Mingmu Dihuang Pill Usage and Dosage 7.5 Preparation Method 7.6 Various Discussions 8 Feeding Mingmu Dihuang Pill of Heting Ji Fang 8. 1 Prescription 8.2 Composition 8.3 Indications 8.4 Mingmu Dihuang Pill Usage and Dosage 8.5 Preparation Method 8.6 Note 9 "Yi Xin Wu" Volume 4 Mingmu Dihuang Pill 9. 1 Prescription 9.2 Composition 9.3 Indication 9.4 Mingmu Dihuang Pill Usage and Dosage 9.5 Preparation Method 65438+ 10.2 Component 10.3 Efficacy 10.4 Indication 10.5 Mingmu Dihuang Pill Usage and Dosage 10.6 Preparation Method/kloc-0. Prescription name 1 1.2 components1.3 efficacy 1 1.4 indications 1 1.5 dosage1/kloc. Pharmacopoeia standard 12. 1 name 12.2 prescription 12.3 preparation method 12.4 character 12.5 identification 12.6 inspection 12.7. .7. 1 wine dogwood meat 12.7. 1 chromatographic conditions and system applicability test12.7.10.2 preparation of reference solution12.7.10.3 test sample. 2.7.2 Cortex Moutan 65438+8+02.7.3 Paeoniflorin 12.7.3. 1 chromatographic conditions and system applicability test 12.7.3.2 Preparation of reference solution12.7.2. 12.9 Usage and dosage 12. 10 specification 12. 16 storage 12. 12 version 13 Chinese medicine label of Mingmu Dihuang Pill/. Type 13.2 pinyin name 13.3 standard number 13.4 prescription 13.5 making method 13.6 Chinese characters 13.7 identification 13.8 inspection/kloc-0. 13. 10 usage and dosage 13. 1 specification 13. 12 storage 14 drug description of Mingmu Dihuang pills14./kloc Product name 14.3 hanyu pinyin 14.4 English name 14.5 components 14.6 characteristics 14.7 action category 14.8 indications/functional indications 14.9 specifications/kloc. Kloc-0/4.654385438+04.14 Interaction between Mingmu Dihuang Pills and Other Drugs14./Pharmacological Effects of Mingmu Dihuang Pills 14. 16 Remarks16

2 English reference Mingmu Dihuang Pill [2 1 Century Bilingual Dictionary of Science and Technology]

Mingmu Dihuang Pill [Terminology Committee of Traditional Chinese Medicine]. Terminology of Traditional Chinese Medicine (2004)]

Mingmu Dihuang Pill [Terminology Committee of Traditional Chinese Medicine]. Terminology of Traditional Chinese Medicine (2004)]

3. Information on retail guidance price of national essential drugs and related national essential drugs of Mingmu Dihuang Pill.

Essential drug serial number

DirectoryNo. Drug name, dosage form and specification Retail unit refers to

Remarks on price category 1033 90 Mingmu Dihuang Pill Honey Pill 9g Pill 1 Chinese patent medicine part * 1034 90 Mingmu Dihuang Pill 54g bottle 5.3 Chinese patent medicine part 1035 90 Mingmu Dihuang Pill 60g bottle 5.8 Chinese patent medicine part 1 036 90 Mingmu Dihuang Pill 90g bottle 8.4 Chinese patent medicine part 65433 bottles 1 1 Chinese patent medicine part 1038 90 Mingmu Dihuang Pill Shuimi Pill 60g bottle 10.7 Chinese patent medicine part * △ 1039 90 Mingmu Dihuang Pill Shuimi Pill 6g bag/kloc. Kloc-0/040 90 Mingmu Dihuang Pill 30g bag 5.6 Chinese patent medicine part pill 40g bottle 7.4 Chinese patent medicine part 1043 90 Mingmu Dihuang Pill 54g bottle 9.7 Chinese patent medicine part 1044 90 Mingmu Dihuang Pill 120g bottle 20.3 Chinese patent medicine part1044 38+0.6 Chinese patent medicine part * △ 1046 90 Mingmu Dihuang Pill Concentrated Pill 120 medicine bottle 7. 1 Chinese patent medicine part 1047 90 Mingmu Dihuang Pill Concentrated Pill 192 medicine bottle/kloc-0.

1. The dosage form specifications marked with "*" in the remarks column in the table are representative products.

2. Specifications of dosage forms with "△" in the remarks column in the table, and other specifications of the same dosage form are tentative prices.

3. The dosage form specifications are indicated in the remarks column. The prices of other specifications in this dosage form are based on the same usage and dosage, and are calculated according to the drug price comparison rules.

4. The "honey pills" marked in the dosage form column include small honey pills and big honey pills.

Summary Mingmu Dihuang Pill is the name of prescription, and there are about 7 prescriptions with the same name.

The main components of Mingmu Dihuang Pill are Radix Rehmanniae Preparata, Cornus officinalis (processed), Cortex Moutan, Rhizoma Dioscoreae, Poria, Alismatis Rhizoma, Fructus Lycii, Flos Chrysanthemi, Radix Angelicae Sinensis, Radix Paeoniae Alba, Fructus Tribuli and Concha Haliotidis (calcined) [1]. Has the effects of nourishing kidney and liver and improving eyesight. For liver and kidney yin deficiency, dark eyes, photophobia, blurred vision, tears in the wind.

The drug standards of People's Republic of China (PRC) and the Ministry of Health of the People's Republic of China contain the ministerial standards of Mingmu Dihuang Pills.

People's Republic of China (PRC) Pharmacopoeia (version 20 10) records the pharmacopoeia standard of Mingmu Dihuang Pills.

5. The Mingmu Dihuang Pill of the five prescriptions in the Inspection Letter (5. 1) consists of Radix Rehmanniae (washed with wine), Rhizoma Dioscoreae, Rhizoma Alismatis, Fructus Corni (washed with wine), Cortex Moutan (washed with wine), Radix Bupleuri, Poria (steamed with milk), Radix Angelicae Sinensis (washed with wine) and Fructus Schisandrae [2].

5.2 Usage and dosage of Mingmu Dihuang Pill is fine powder, refined honey is pill, and buttonwood is big. Every time I take San Qian, I will send a light salt water soup on an empty stomach [2].

5.3 Efficacy and Indication Mingmu Dihuang Pill has the effect of nourishing liver and kidney [2].

It is unknown to treat kidney deficiency with black eyes [2]. Treatment of cloud shift, cyanosis, high wind cataract [3].

6 "Bubaibing Rejuvenation" Volume 5 Mingmu Dihuang Pill 6. 1 FangmingMingmu Dihuang Pill

6.2 Four parts of Radix Rehmanniae (washed with wine), four parts of Radix Rehmanniae Preparata, two parts of Rhizoma Anemarrhenae (fried with salt water), two parts of Cortex Phellodendri (fried with wine), two parts of Semen Cuscutae (processed with wine), two parts of Radix Angelicae Pubescentis 1 2, two parts of Fructus Lycii, three parts of Radix Cyathulae (washed with wine) and three parts of Semen Astragali (fried).

6.3 Efficacy: WuMingmu Dihuang Pill in BuBaiBing Rejuvenation has the effects of producing essence and nourishing blood, tonifying kidney and benefiting liver, expelling wind and improving eyesight.

6.4 Indications: WuMingmu Dihuang Pill in BuBaiBing Rejuvenation is used for blindfolding, shedding tears, and treating red eyes.

6.5 Usage and dosage of Mingmu Dihuang Pills: 80 pills each time, with light salt in summer and wine in other months.

6.6 The preparation method is fine powder, and refined honey is pill, which is as big as buttonwood.

6.7 The amount of dodder in the notes was originally small.

7 Six Books on Medical Strategies Volume 2 1 Mingmu Dihuang Pill 7. 1 Fangming Mingmu Dihuang Pill

7.2 consists of five parts of Radix Rehmanniae Preparata, two parts of Cornus officinalis, two parts of Alisma orientalis 1, two parts of Cortex Moutan 1, two parts of Poria (wood removal), three parts of Chinese yam (fried), three parts of Angelica sinensis and Ligusticum wallichii 1, three parts of Ophiopogon japonicus (heart removal) and three parts of Dendrobium.

7.3 Indications: Twenty-one Mingmu Dihuang Pill in Six Books of Medical Policy is suitable for patients with deficiency of liver and kidney, dark eyes and weak pulse.

7.4 Mingmu Dihuang Pill Usage and Dosage: Take 3 yuan with boiling water every time.

7.5 The preparation method is powder and refined honey is pill.

7.6 The factions discussed the deficiency of liver and kidney, and the essence and blood could not be served, so the eyes were dim and things were unclear. Radix Rehmanniae Preparata tonifies the kidney and nourishes the liver, Cornus officinalis nourishes the essence and secret qi, Cortex Moutan cools the blood and relieves yin fire, Rhizoma Dioscoreae tonifies the spleen and benefits the true yin, Radix Angelicae Sinensis nourishes the blood and nourishes the liver, Rhizoma Chuanxiong promotes blood circulation and awakens the brain, Alismatis Rhizoma clears away damp-heat, tranquilizes the mind, Radix Ophiopogonis clears the heart and moistens dryness, and Dendrobium candidum clears heat and nourishes yin. Under the honey pill, the liver and kidney nourish essence and blood, and the eyes are clear and clear. The agent for tonifying kidney, nourishing liver and clearing damp-heat is a special prescription for treating liver and kidney deficiency and dark eyes.

8 Mingmu Dihuang Pills in Feeding Crane Pavilion Ji Fang 8. 1 Fangming Mingmu Dihuang Pills

8.2 The ingredient of Liuwei Pill is 1, including 3 parts of chamomile, 2 parts of Lycium barbarum, concha Haliotidis and Tribulus terrestris.

8.3 Mingmu Dihuang Pill, mainly used to feed Heting Ji Fang, is mainly used to treat deficiency of liver and kidney in men and women, invasion of pathogenic wind, hot air attacking people, fear of yang and shame of brightness, dilated pupils, blurred vision, tears in the wind, endogenous obstruction, long-term failure to return the eyes, and all eye diseases.

8.4 Usage and dosage of Mingmu Dihuang Pill: Take 34 yuan and send light salt water soup.

8.5 Preparation method: honey pill 5 points, water method 6 points.

8.6 The amount of concha Haliotidis and Tribulus terrestris in the notes was originally small.

9 Medical Understanding Volume 4 Mingmu Dihuang Pills 9. 1 Fangming Mingmu Dihuang Pills

9.2 Radix Rehmanniae (washed with wine) 1 kg, Achyranthes bidentata, Ophiopogon japonicus, Angelica sinensis and Lycium barbarum.

9.3 Indications: Mingmu Dihuang Pill, Volume IV of Yi Xin Kai Wu, is mainly used for cataract, shyness and depression.

9.4 Mingmu Dihuang Pill Usage and Dosage: Take 3 yuan with boiling water every time.

9.5 The preparation method takes Ganjuhua 8 as two soups and honey as pills.

10 Mingmu Dihuang Pill 10. 1 Fangming Mingmu Dihuang Pill in Beijing-selected TCM prescriptions.

10.2 is composed of 288 Rehmannia glutinosa, 288 Rehmannia glutinosa, 72 Fructus Aurantii (fried), 72 Radix Saposhnikoviae, 54 Achyranthis Radix, 36 almond (peeled and fried), 24 Dendrobium, 48 Cortex Phellodendri, 48 Rhizoma Anemarrhenae, 72 Flos Chrysanthemi and 36 Cortex Moutan.

10.3 Efficacy Mingmu Dihuang Pill has the effects of nourishing yin, clearing away heat, calming the liver and improving eyesight.

10.4 Mingmu Dihuang Pill indicated in Selected Works of Prescriptions of Traditional Chinese Medicine in Beijing is mainly used for treating yin deficiency and liver heat, wind and fire, red eyes and watery eyes, and blurred vision.

10.5 Mingmu Dihuang Pill Usage and Dosage: Take 1 pill twice a day with warm boiled water.

The preparation method of 10.6 is fine powder, refined honey is pills, and the weight is 3 yuan.

Mingmu Dihuang Pill 1 1 Chinese Medicine Prescription 1 1. 1 Fangming Mingmu Dihuang Pill.

1 1.2 is composed of 8 liang of Radix Rehmanniae Preparata, 4 liang of Cornus officinalis, 4 liang of Rhizoma Dioscoreae, 3 liang of Cortex Moutan (fried with wine), 3 liang of Poria, 3 liang of Rhizoma Alismatis (fried with salt water), 3 liang of Radix Angelicae Sinensis, 3 liang of Radix Paeoniae Alba, 3 liang of Fructus Lycii, 3 liang of Flos Chrysanthemi, 3 liang of Fructus Tribuli and 3 liang of Concha Haliotidis.

1 1.3 efficacy Mingmu Dihuang Pill in traditional Chinese medicine prescription has the effects of calming liver and nourishing kidney, expelling wind and improving eyesight.

1 1.4 Mingmu Dihuang Pill, mainly used in traditional Chinese medicine prescriptions, is mainly used for treating deficiency of both liver and kidney, red eyes, tears in the wind and blurred vision.

Administration and dosage 1 1.5 Mingmu Dihuang Pill is taken with boiled water every time in 2 yuan, 1 twice a day.

1 1.6 Preparation method: Mash Radix Rehmanniae Preparata and Corni Fructus, mix with other medicines, dry in the sun, grind into powder, and make cold water pills, such as mung beans, about 36 pills.

Pharmacopoeia standard 12 Mingmu Dihuang Pill 12. 1 is called Mingmu Dihuang Pill.

Mingmu Dihuang Pill

12.2 prescription: Radix Rehmanniae Preparata160g, Fructus Evodiae 80g, Cortex Moutan 60g, Rhizoma Dioscoreae 80g, Poria 60g, Rhizoma Alismatis 60g, Fructus Lycii 60g, Flos Chrysanthemi 60g, Radix Angelicae Sinensis 60g, Radix Paeoniae Alba 60g, Fructus Tribuli 60g, and Concha Haliotidis preparata 80g.

12.3 Prepare the above twelve medicinal materials, pulverize them into fine powder, sieve them and mix them evenly. Granulating each100g powder with 35-50g refined honey and appropriate amount of water, and drying to make honeyed pills; Or adding refined honey 90- 1 10g to make small honey pills or big honey pills.

12.4 characteristics This product is a dark brown to black honey pill, a small black honey pill or a big honey pill; The gas is slightly fragrant, and the taste is sweet first and then bitter.

12.5 Identification (1) Take this product and observe it under the microscope: the starch granules are triangular oval or oblong, with a diameter of 24 ~ 40μ m, and the umbilical point is short slit or herringbone (yam). Irregular branched mass is colorless and soluble in chloral hydrate test solution; The mycelium is colorless or light brown, with a diameter of 4 ~ 6 microns (Poria cocos). The parenchyma is grayish brown to dark brown, and the cells are mostly shriveled, containing brown nuclei (Radix Rehmanniae Preparata). The epidermal cells of pericarp are orange-yellow, with polygonal surface and beaded vertical wall (wine dogwood meat). Thin-walled cells are round with oval pits and integrated pits; The vertical peripheral wall of the cells in the endodermis is wavy, thick and lignified, with sparse holes and grooves (Alisma orientalis). The surface of stone cells in seed coat is irregular polygon, with thick wall, wavy curvature and clear bedding (Lycium barbarum). Pollen grains are round, with a diameter of 24 ~ 34μ m, with thorns on the outer wall, a length of 3 ~ 5μ m and three germination holes (chrysanthemum). The fiber diameter is 1.5 ~ 35 microns, the wall thickness is slightly lignified, and there are large round holes (peony). The pericarp fiber is lignified, and the upper and lower layers are staggered (Tribulus terrestris). Irregular lumps are dark gray and opaque, and bubbles are generated after adding acid (calcined concha Haliotidis).

(2) Take this honey pill 18g and grind it into powder; Or take 24g small honey pills or big honey pills and cut them into pieces. Add 10ml ether to make it moist, add 40 ml petroleum ether (30 ~ 60℃), ultrasonically treat15min, stand overnight, filter, evaporate the filtrate, and add 2ml acetone to dissolve the residue as the test solution. In addition, acetone was added to paeonol reference substance to prepare a solution containing 1mg per 1ml as reference substance solution. According to the test of thin-layer chromatography (Appendix ⅵ b of Pharmacopoeia Part I, 20 10), 6μl of the test solution and 4μl of the reference solution were respectively absorbed, spread on the same silica gel G thin-layer plate with cyclohexane-ethyl acetate (3: 1) as the developing agent, taken out, dried, sprayed with 5% ferric chloride ethanol solution of hydrochloric acid, and dried at/kloc. In the chromatogram of the test sample, spots with the same color appear in the position corresponding to the chromatogram of the control sample.

(3) Take 6g of this honey pill and grind it into powder; Or take 9g of small honeyed pills or big honeyed pills, cut into pieces, add 5g of diatomite, grind evenly, and dry. Add 30ml of n-hexane, perform ultrasonic treatment for 65438 0.5 minutes, filter, and concentrate the filtrate to about 65438±0ml as the test solution. In addition, 65438 0 g of Angelica sinensis was taken as the control medicinal material, and 20ml of n-hexane was added to prepare the control medicinal material solution by the same method. According to the test of thin-layer chromatography (Appendix ⅵ b of Pharmacopoeia Part I, 20 10), 4μl of the above two solutions were absorbed, spotted on the same silica gel G thin-layer plate, developed with n-hexane-ethyl acetate (9: 1) as the developing agent, taken out, dried, and examined under ultraviolet lamp (365nm). In the chromatogram of the test sample, fluorescent spots with the same color appear at the positions corresponding to the chromatogram of the control medicinal materials.

(4) Take 6g of this honey pill and grind it into powder; Or take 9g small honeyed pills or big honeyed pills, slice them, add 4g diatomite and grind them evenly. Add 50 ml of ethanol, perform ultrasonic treatment for 20 minutes, filter, evaporate the filtrate to dryness, add 20 ml of water to dissolve the residue, shake and extract with water saturated n-butanol for 3 times, 20 ml each time, combine the n-butanol extractive solutions, evaporate to dryness, and add 1 ml of ethanol to dissolve the residue as a test solution. In addition, paeoniflorin reference substance was added with ethanol to prepare a solution containing 1mg per 1ml as the reference substance solution. According to the test of thin-layer chromatography (appendix ⅵ b of Pharmacopoeia I, 20 10), absorb 5μl of the above two solutions, respectively spot them on the same silica gel G thin-layer plate, and use chloroform-ethyl acetate-methanol-formic acid (40: 5: 10: 0.2) as the developing agent, unfold, take out, dry and spray. In the chromatogram of the test sample, spots with the same color appear in the position corresponding to the chromatogram of the control sample.

12.6 the inspection shall comply with the relevant provisions under pills (appendix 1A of China Pharmacopoeia I, 20 10).

12.7 content determination 12.7. 1 Evodia rutaecarpa was determined by high performance liquid chromatography (appendix 6 d of Pharmacopoeia I, 20 10).

12.7. 1. 1 chromatographic conditions and system applicability test with octadecylsilane bonded silica gel as filler; The mobile phase is tetrahydrofuran-acetonitrile-methanol -0.05% phosphoric acid solution (1: 6: 3: 90). The detection wavelength is 236 nm; ; The column temperature is 40℃. According to the peak of loganin, the theoretical plate number should not be less than 4000.

12.7.10.2 preparation of reference substance solution: take a proper amount of loganin reference substance, weigh it accurately, and add 50% methanol to make a solution containing 20μg per 1ml.

12.7. 1.3 Preparation of test solution Take this honey pill, grind it, take 1.3g, and weigh it accurately; Or take a small honey pill or a large honey pill with different weight, cut into pieces, mix well, take 65438±0.8g, weigh accurately, put it in a conical flask with a stopper, add 50 ml of 50% methanol accurately, plug tightly, weigh, ultrasonically treat for 65,438 05 minutes, and heat and reflux for 65,438 minutes. Accurately measure 10ml continuous filtrate, add it to neutral alumina column (100 ~ 200 mesh, 4g, inner diameter 1cm), elute with 50ml of 40% methanol, collect effluent and eluent, evaporate to dryness, dissolve the residue with appropriate amount of 50% methanol, and transfer it to 5ml volumetric flask.

12.7. 1.4 determination method accurately absorb 10μl control solution and test solution, respectively, and inject them into a liquid chromatograph for determination.

This product contains Evodia rutaecarpa and loganin (C 17H26O 10), and the honey pill per kloc-0/g shall not be less than 0.30mg, the millet pill per kloc-0/g shall not be less than 0.22mg and the damiwan pill shall not be less than 2.0 mg.

12.7.2 Cortex Moutan was determined by high performance liquid chromatography (Appendix VI D of Pharmacopoeia I, 20 10).

12.7.2. 1 chromatographic conditions and system applicability test with octadecylsilane bonded silica gel as filler; Methanol-water (70: 30) is the mobile phase; The detection wavelength is 274 nm. The theoretical plate number should be not less than 3500 calculated by paeonol peak.

12.7.2.2 preparation of reference substance solution take appropriate amount of paeonol reference substance, weigh it accurately, and add methanol to make a solution of15 μ g.

12.7.2.3 Preparation of test solution Take this honey pill, grind it, take 0.5g, and weigh it accurately; Or take small honey pills or big honey pills with poor weight, chop them up, mix them evenly, take 0.5g, and weigh them accurately. Put it in a conical flask with a stopper, add 50 ml of 70% methanol, plug it tightly, weigh it, perform ultrasonic treatment (power 250W, frequency 33 kHz) for 45 minutes, let it cool, weigh it again, make up the weight loss with 70% methanol, shake it evenly, filter it, and take the filtrate.

12.7.2.4 determination method accurately suck 10μl control solution and 20μl test solution respectively, inject them into liquid chromatograph and determine.

This product contains paeonol (C9H 10O3), and the honey pill shall not be less than 0.50mgper1g; Xiaomi pill shall not be less than 0.40 mg per1g; Damivan shall not be less than 3.6 mg per pill.

12.7.3 determination of paeoniflorin by high performance liquid chromatography (appendix ⅵ D of Pharmacopoeia I, 20 10 edition).

12.7.3. 1 chromatographic conditions and system applicability test with octadecylsilane bonded silica gel as filler; Acetonitrile -0. 1% phosphoric acid solution (14: 86) was used as the mobile phase. The detection wavelength is 230 nm. The theoretical plate number should be not less than 4500 calculated by paeoniflorin peak.

12.7.3.2 preparation of reference solution take a proper amount of paeoniflorin reference substance, weigh it accurately, and add methanol to make a solution containing 50μg per 1ml.

12.7.3.3 preparation of test solution accurately measure 25ml of test solution under the content determination of cortex moutan, evaporate to dryness, add 25ml of water to the residue, dissolve it with slight heat, let it cool, shake and extract it with water-saturated n-butanol for three times, 25ml each time, combine the n-butanol extracts, evaporate to dryness, dissolve the residue with methanol, transfer it to a 5ml volumetric flask, add methanol to the scale, and shake well.

12.7.3.4 determination method accurately absorb 10μl control solution and test solution respectively, inject them into liquid chromatograph, and determine.

This product contains Radix Paeoniae Alba and Cortex Moutan, calculated as paeoniflorin (C23H28O 1 1), and the honey pill shall not be less than 0.80 mg per1g; Xiaomi Pill shall not be less than 0.60mg per kloc-0/g and Damivan shall not be less than 5.4 mg per pill.

12.8 function indications: nourishing kidney, nourishing liver and improving eyesight. For liver and kidney yin deficiency, dark eyes, photophobia, blurred vision, tears in the wind.

12.9 Administration and dosage taken orally. Shuimi pill 6g once, Xiaomi pill 9g once, Damei pill 1 pill once, twice a day.

12. 10 honey pill? Each pill weighs 9 grams.

12. 1 1 storage seal.

12. 12 Edition People's Republic of China (PRC) Pharmacopoeia 20 10 Edition

13 Chinese medicine standard of Mingmu Dihuang Pill 13.6438+0 concentrated pill.

13.2 Pinyin Name Mingmu Dihuang Pill

13.3 standard number WS3B 175594

13.4 Prescription Radix Rehmanniae Preparata? 160g Cornus officinalis (domestic)? 80g peony bark? 60g yam 80g poria cocos 60g Alisma 60g Lycium barbarum? Chrysanthemum 60g Angelica 60g Paeonia lactiflora 60g Tribulus 60g Concha Haliotidis (calcined)? 80 grams

13.5 Take the above twelve herbs, slice Radix Rehmanniae Preparata, add water and decoct for three times, the first time is 3 hours, the second time is 2 hours, and the third time is 1 hour, combine decoctions, filter, and concentrate the filtrate to the relative density of1.30 ~1.35 (20 Using Cornus officinalis, Cortex Moutan, Radix Paeoniae Alba, Flos Chrysanthemi, Radix Angelicae Sinensis 40g, Fructus Tribuli, and Fructus Lycii as solvents, and Alismatis Rhizoma as solvents, respectively soak for 24 hours according to the percolation method under the fluid extract and the extract (17 page), then percolate, collect and combine percolates, recover ethanol, and concentrate. 20 grams of Rhizoma Dioscoreae, Poria, Concha Haliotidis and Radix Angelicae Sinensis are crushed into fine powder, mixed with the above fluid extract, made into concentrated pills, dried and polished.

13.6 characteristics this product is a dark brown concentrated pill; The gas is slightly fragrant, and the taste is sweet first and then bitter.

13.7 Identification (1) Take this product and observe it under the microscope: the irregular branched block is colorless and soluble in chloral hydrate; The mycelium is colorless or light brown, with a diameter of 4 ~ 6 μ m, and there are 80 ~? 240μm, and the diameter of needle crystal is 2 ~ 8 μ m. Thin-walled cells are spindle-shaped, with a slightly thicker wall and a very fine oblique staggered structure.

(2) Take 2g of this product and add dilute hydrochloric acid, a large number of bubbles will appear. When this gas meets the calcium hydroxide test solution, it will become turbid. Add 2ml of water, stir, filter, adjust the filtrate to weak alkalinity with ammonia solution, and add 1 drop of ammonium oxalate solution to generate white precipitate.

13.8 The inspection shall comply with the relevant regulations of Pills (Appendix 8).

13.9 function indications: nourishing kidney, nourishing liver and improving eyesight. For liver and kidney yin deficiency, dark eyes, photophobia, blurred vision, tears in the wind.

Administration and dosage: 13. 10 orally, 8 ~ 10 capsules at a time, three times a day.

13. 1 1 specifications Every 8 pills is equivalent to 3g of the original crude drug.

13. 12 storage and sealing.

14 drug description of Mingmu Dihuang Pill 14. 1 drug type traditional Chinese medicine

14.2 drug name Mingmu Dihuang Pill

/KOOC-0/4.3 Chinese Pinyin of Drugs/KOOC-0/4.4 English Name of Drugs/KOOC-0/4.5 Components/KOOC-0/4.6 Properties/KOOC-0/4.7 Action Category/KOOC-0/4.8 Indications/Functions: Nourishing kidney, nourishing liver and improving eyesight. For liver and kidney yin deficiency, dark eyes, photophobia, blurred vision, tears in the wind.

14.9 specification 14. 10 Mingmu Dihuang Pill for oral administration. Honey pills are 6 grams at a time, twice a day.

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14. 1 1 contraindications 14. 12 Adverse reactions 14. 13 Precautions 1. Avoid smoking, drinking and spicy food.

Don't take it when you have a cold. People suffering from serious chronic diseases such as hypertension, heart disease, liver disease, diabetes and kidney disease should take it under the guidance of a doctor.

3. Children, pregnant women, lactating women, the elderly and the infirm, and loose stool with spleen deficiency should be taken under the guidance of a doctor.

Patients with headache, eye swelling, iridescence or glaucoma should go to the hospital.

People with ophthalmia or fundus diseases should go to the hospital.

6. If your eyesight drops obviously after taking the medicine, you should go to the hospital.

7. If the symptoms are not relieved after taking the medicine for 2 weeks, you should go to the hospital.

8. It is forbidden for those who are allergic to this product, and should be used with caution for those who are allergic.

9. It is forbidden to use this product when its characteristics change.

10. Children must use it under the supervision of adults.

1 1. Please keep this product out of the reach of children.

12. If you are using other drugs, please consult a doctor or pharmacist before using this product.

14. 14 If used together with other drugs, drug interactions may occur. Please consult a doctor or pharmacist for details.

14. 15 Pharmacological Effects of Mingmu Dihuang Pills 14. 16 Remarks