These papers cover the pharmacological effects of curcumin on antioxidation, anti-inflammation, anti-cancer, neuroprotection such as children's anti-Alzheimer's disease and anti-autism, repair and protection of liver function, anti-virus such as anti-AIDS, anti-cardiovascular disease and anti-autoimmune disease.
In 2007, the most authoritative National Health Agency (NIH) in the United States approved the clinical trials of curcumin for rectal cancer, pancreatic cancer, Alzheimer's disease and multiple myeloma. Subsequently, clinical trials of breast cancer, osteoarthritis and other diseases were also approved for implementation.
0 1. What is curcumin?
Curcumin is a yellow pigment extracted from turmeric rhizome, which is slightly bitter and insoluble in water.
Turmeric is one of the 250 medicinal plants mentioned in ancient medical books, and its medicinal value appears on the wedge-shaped stone tablet compiled by King Azubani (669-627 BC) (named Assyrian herb by the discoverer R.C. Thompson).
The curative effect of turmeric has been observed in two classical medical systems in the East: traditional Chinese medicine and Ayurvedic medicine (Indian traditional medicine), and the curative effect of turmeric is rarely mentioned in ancient Chinese medicine books. However, turmeric is one of the main components of Ayurvedic medicine, which has been used for more than 6000 years and is the most widely used medicine in Ayurvedic medicine. It believes that turmeric has the efficacy of purifying the body and treating many diseases, such as digestive system diseases, fever, infection, arthritis, dysentery, jaundice and other liver diseases. Turmeric is also a part of the daily diet of Indians, taking1.5 ~ 2g of turmeric every day.
The anti-cancer effect of curcumin in animal experiments has been clear, and it is found that curcumin can prevent some cancers caused by carcinogens in rats. These studies also found that curcumin can effectively prevent and treat some cancers, including gastric cancer, intestinal cancer, small intestinal cancer, skin cancer and liver cancer, regardless of whether these cancers are in the initial stage or clinical development stage. These results have also been confirmed by other studies: curcumin can inhibit the growth of leukemia, colon cancer, breast cancer and other cancer cells.
Generally speaking, its function seems to be related to the ingredients needed to hinder the survival of some cancers, which can make cancer cells autophagy and die inevitably. The study also found that curcumin can cut off the energy supply of tumors by inhibiting the growth of new blood vessels.
Mitch Gaynor, a famous American doctor of integrated traditional Chinese and western medicine, believes that curcumin is the super nemesis of tumor, and there are at least 20 ways for curcumin to inhibit precancerous lesions and tumor cell lines. The following is an overview of curcumin inhibiting cancer cells:
1 Inhibits nuclear transcription factor NF-kB, which is a protein complex associated with cancer and regulates inflammation and immune response.
2 Inhibit advanced glycation end products (AGEs), which is a glycotoxin related to oxidative stress (cancer cells contain a lot of AGEs).
3 Prevent cancer cells from spreading
Attacks cancer cells without affecting normal tissues.
Promote the sensitivity of cancer cells to anticancer drugs and accelerate the death of cancer cells.
6 Inhibition of cancer cell metastasis through various mechanisms.
At present, there are more than 20 studies on the therapeutic effects of turmeric and curcumin in different cancers (colon cancer, breast cancer, pancreatic cancer and melanoma). Previous research results are encouraging, because turmeric and curcumin have no side effects (or few) at high doses, and some patients respond well to this treatment.
A study on patients with advanced pancreatic cancer found that the application of curcumin can significantly reduce the tumor size of patients (73%), and finally stabilize the disease. These remarkable results show that this substance plays a powerful role in cancer prevention.
The medicinal value of turmeric has been widely recognized by the international medical community, and it is clinically used for anti-tumor, anti-oxidation, blood lipid reduction, anti-inflammation, anti-bacteria, positive and negative pain, anticoagulation, liver protection, anti-bacteria, mites and so on. Taking curcumin should first pay attention to its solubility and absorption and utilization effect in human body. The solubility of turmeric extract from Saudi Arabia is 18 times that of ordinary curcumin. At present, it is available in the official enterprise store of Echo.
In modern medical and pharmaceutical research, curcumin not only has high anticancer activity, but also has many pharmacological effects, including anti-blood test, cholesterol reduction and anti-inflammatory reaction (several times that of vitamin E).