What is the medical principle of "fighting poison with poison"?

There is often such a plot in novels: the protagonist is poisoned by the wicked for various reasons and has nowhere to be cured. Later, by coincidence, another kind of poison came to me. The two poisons are not dead, but the latter has become the antidote to the former, which makes readers sigh that God never shuts one door but he opens another-this is "fighting poison with poison".

"Fighting poison with poison" comes from the Song Dynasty's History of a Nest on the Road: "If you rob a village, attack a plot, and then you can't do it." Fighting poison with poison, benevolent people have different opinions. " Refers to the treatment of toxic sores with poison. Metaphor is to use bad things or their own contradictions to oppose bad things, or to use vicious means to deal with vicious means. Ming Dow Zong Yi's Record of Dropping out of Farming: "Bone rhinoceros is poisonous, which can detoxify and cover it with poison to resist poison." Feng Ming's magnum "Awakening the World, Keeping Words, Chen Duoshou's Life and Death Couple": "I took poisoned wine today, but I didn't expect it, just like the medical book" Fighting poison with poison ". A lot of evil blood came in and out of my skin, the poisonous gas was exhausted, and even the boils were getting better. " Zhang Qing's Twenty-two Years of Daoguang: "Zhang belongs to the army, so if the younger generation can know about theft, they will be incorporated into the camp and fight poison with poison, which also has disadvantages."

The explanation of the first word "poison" in Shuo Wen Jie Zi is: "Poison, strong and harmful, often comes from poison." It can be seen that this "poison" can refer to drugs, usually referring to drugs with more serious toxicity. Bing Wang's Note: "Fight the disease with poison."

The Analects of Confucius says, "Poison is a powerful medicine." It can also refer to the methods and means of treating diseases.

Shuo Wen Tong Xun Ding Sheng: "Poison is used as a prison." "Supervision" and "governance" are the same meaning. Attack and treatment, in addition to attack and diarrhea, can also refer to some special treatment methods, as opposed to tonic methods. Activating blood circulation to remove blood stasis, removing blood stasis, softening and resolving hard mass, resolving phlegm, dredging interior and attacking interior, resolving hard mass, etc. can all be called "attacking" method.

"Zhou Li Tianguan": "All treatments are attacked by five poisons."

"On the Origin and Development of Medicine": "If you are injured by real evil, you should attack it urgently, so you should use strong medicine." You can make an example. The same is true of other therapies. For example, "Spirit Pivot Madness" said: "Zuo Qiang attacked his right, right attacked his left, and the blood stopped."

Treatise on Febrile Diseases treats sun diseases based on syndrome differentiation: "The pulse with slight number should not be moxibustion. Because fire is evil, annoying and rebellious, pursuing emptiness and seeking truth, blood scattered in the pulse. Although the internal fire is small, it is powerful. " The second kind of "poison" not only refers to a dangerous, rapid and critical disease, but also refers to some diseases caused by "poison", such as violence, infection, filth, lingering and evil.

In fact, although it is not as exaggerated as described in the novel, art originates from life, and "fighting poison with poison" is also an important and unique therapy of traditional Chinese medicine. The germination of his thoughts can be traced back to Zhouyi. Ganyi: "Respond with one voice and seek with the same spirit. When the water is wet, the fire is dry. " It means that everything is interrelated in all aspects. As long as it is the same at a certain point, it will produce a sense of affinity, complementarity, coordination and beneficial contact and function in a certain aspect.

"Fighting poison with poison" can be regarded as "seeking the same gas", and it is also a phenomenon of mutual development and mutual resistance in basic principle. Things born from the same root have similar blending properties. The Book of Songs: "What about Wako?" This is not an axe. Zheng Xuan's Note in the Eastern Han Dynasty: "The only way to cut Ke is to use an axe, and this is to seek its kind. "In the same way, the poison of traditional Chinese medicine is that drugs and pathogenic qi are" the same ",and" qi is similar, so they are excluded ",so as to attack the poison, so as to achieve the purpose of taking the partial as the whole and bringing out the best in each other.

The idea of traditional Chinese medicine fighting poison with poison originated from Su Wen's Liu Zhengyuan's Collection of Great Works. "Zhou Shenzhai's suicide note" is interpreted as: "Covering a female corpse is harmless and poisonous. Generally, if the fetus is sick, the fetus should be given priority. If the fetus is uneasy because of illness, it should be treated in an emergency, so it is also possible to use poison. " It can be seen that as long as drugs are used properly, even poisons, as long as they are used properly, will not cause harm to the body. "Flexible medical methods and disadvantages of medication": "When you are sick, aconite arsenic is a treasure; If you are sick, Shenqi velvet antler medlar is arsenic. "

Medicine can be a disease, and poison is a holy medicine; Medicine is not symptomatic, even if it is slight, it will hurt the body. It shows that as long as the body has diseases, even during pregnancy and perinatal period, it can be treated with drugs. It is emphasized that poison is relative, and if used reasonably, it is toxic and non-toxic. If used improperly, it can be toxic or non-toxic. In addition, Su Wen's theory of dirty qi, theory of attacking evil with poison and Su Wen's theory of truth, and more importantly, they also provide circumstantial evidence for the formation and application of the law of fighting poison with poison.

In Shennong's Classic of Materia Medica and Treatise on Febrile Diseases, the use of highly toxic Chinese medicines such as aconite, aconite and croton is the specific application of fighting poison with poison.

During the Wei, Jin, Southern and Northern Dynasties, there were records of "fighting poison with poison" and "fighting poison with poison". There is a saying in Luo's Solemn Convenient Sutra: "You are still stung by a snake, and the poison is destroyed by poison. Ge Hong's "Elbow Queen" discusses that "I want to recover, but I also want to fight poison with poison", and there is a treatment method of "killing the dog, taking the brain to nourish the heart, and then not recurring". Sun Simiao inoculated the pus juice of patients with sores under the skin of healthy people to prevent smallpox. Although it is not explicitly said that "fight poison with poison". Sun Simiao's "Hai Yin Jingwei" treats eye diseases with high exophthalmos and sharp rotation, which is dangerous and harmful. It is said that this is "fighting poison with poison", and it is an early user of "fighting poison with poison" in Chinese medicine literature.

Liu Zongyuan's Snake Catcher said: "If wax is used as bait, it can kill strong wind, contracture, fistula, tendons and three insects." This not only summarizes the role of Yongzhou poisonous snake in treating many diseases, but also proves the application of fighting poison with poison from one side.

During this period, the method of fighting poison with poison has been expanded and applied, and its treatment thought has been clearly reflected. The theory of "fighting poison with poison" and the idea of "fighting poison with poison" have expanded the scope of treatment of this law.

By the Tang and Song Dynasties, the therapy of fighting poison with poison had been deeply developed. Ke Qin, a Zen master in the Song Dynasty, quoted "Quotations from Buddhist Monks in Wuyuan" and said, "Speak with words, seize the opportunity with the opportunity, fight poison with poison, and break with use." It is a metaphor to subdue the other side by the means used by the other side, or to overcome its delusion by its mistakes, which expands the scope of application of fighting poison with poison.

"Wei Ji Bao Shu" clearly expounded the application of drug "fight poison with poison" earlier. It says: "A violent disease is a violent medicine, and this so-called fight poison with poison"; "Is to take medicine according to the condition, at the beginning of two dollars, such as San Qian Wuli, Wuli four dollars, six dollars in the morning and evening. To stop these two things, it is also said that fighting poison with poison. " The application principle of fighting poison with poison is clarified, and the specific use method is formulated.

Yuan Zeng's Talking about Living Young People records the treatment of children's hot flashes with pear juice drinks. The medicines used are Bupleurum, Ginseng Radix, Scutellariae Radix, Radix Peucedani, Radix Gentianae Macrophyllae, Glycyrrhrizae Radix, Artemisia annua, one piece of lotus root, one piece of pear, two pieces of mint and one inch of rehmannia root, and each piece is decocted in half. It is said that this prescription is similar to malaria in treating spleen accumulation due to cold and heat. It is believed that this syndrome is due to the fact that the temper is superior to yin and yang, the cold nature is prior, and yin is more than yang; Its heat is in the back, and yang is abundant in yin. After the party, I wrote a cloud: "Drink pear pulp, fight poison with poison. Artemisia annua is used as medicine to keep out the cold, and its heat is absent, and its coldness will not be added. Nature is glorious and harmonious, yin and yang are one, and cold and heat are not there. " This prescription does not blindly use poison, but the author also said that it is not necessary to use poison to fight poison with poison. Treating diseases with symptoms and treating human diseases with medicinal properties also belongs to fighting poison with poison, so that the method of fighting poison with poison is deepened and expanded. From "fighting violence with violence" to "fighting poison with poison", it is extended to symptomatic treatment or treating diseases with the help of drugs.

The Sanguis Draxonis Ointment in Essentials of Surgery is composed of drugs such as nidus vespae and Huang Dan, and the cloud "Sanguis Draxonis Ointment, Fighting poison with poison" is injected after prescription. Xiao Jie Huadu Powder in Shiyidexiao Prescription can treat acne before it occurs, and "fight poison with poison, even if it comes out soon, there is no evil disease", which makes the anti-poison directly transition from the level of treatment thought and treatment principle to clinical application.

From the Ming and Qing Dynasties, it was a rich and perfect period of "fighting poison with poison".

Compendium of Materia Medica records many traditional Chinese medicines that fight poison with poison, such as snake horn "detumescence and detoxification, fight poison with poison"; Beehives are "used for diseases such as surgery and dentistry, and also used to fight poison with poison and kill insects"; Aconitum "opens stubborn phlegm, cures stubborn sores, and fights poison with poison." Ye used scorpion, beehive, earthworm and other insect drugs to treat chronic pain, malaria mother, accumulation, hysteria and other intractable diseases according to "Li Zhou's poison attacks the disease, and the blood of insects and ants attacks the evil knot", which provided a reference for selecting insect drugs to treat intractable diseases.

At this time, many prescriptions with the effect of "fighting poison with poison" appeared. The core drug "Shengshengru" in Chen Sicheng's Secret Records is made of drugs such as arsenic and calomel, which has the efficacy of "attacking evil with poison" and "treating stubborn poison and stubborn tinea". Chen Shigong's "authentic technique" and "toad venom pill" used calomel, realgar, toad venom and other highly toxic Chinese medicines, and mainly took orally. After the prescription, it is indicated that "there is indeed the power of rebirth, which is the medicine for evil diseases". Gu Shicheng's "The Complete Book of Choosing Doctors" deified Dan, which cured all unknown swelling, and took it immediately at the beginning. "Fight poison with poison, cut hard and guide stagnation like a god". Zhang Xichun's "Rushui Dan" contains drugs such as net calomel, net red powder and nidus vespae to treat "bayberry sore poison, which spreads all over the body and goes deep into the bone marrow". These are the concrete applications of "fighting poison with poison" therapy in traditional Chinese medicine.

In clinical application, the method of attacking poison with poison is applied to various clinical departments.

In the treatment of rheumatism, typhoid fever and chronic joint pain, the revised Treatise on Febrile Diseases pointed out: "Evil poison should be retained, and the law should fight poison with poison." Medical books also record that "fighting poison with poison causes acne, such as pangolin, human teeth and cicada slough".

The article "Guanzhong" in Chen Shiduo's New Compendium of Materia Medica clearly puts forward that "this thing is toxic and can detoxify, so-called fighting poison with poison"; It is believed that toad venom "detoxifies like a god, and makes drugs with poison." Explain that aconite root "cures poison with poison, that is, aconite root is toxic to remove poison and non-toxic to cure poison". At this point, the application of fighting poison with poison is gradually becoming perfect and refined.

To sum up, the development of the method of fighting poison with poison, like other contents of Chinese medicine theory, has experienced the development process from simple to complex, from normative to flexible, from vague to clear, from local to whole, and its thought is vivid and forward, which embodies the unique achievements of Chinese medicine. In modern times, the research on fighting poison with poison has become more and more clear, which is quite effective in treating malignant tumors, AIDS, skin diseases and other diseases. In modern life science, fighting poison with poison is also the opposition between elements. Through the definition of antagonism between components, we can think that biological effect is a summary of clinical practice today.

As the western proverb says, "Your poison is his honey." Some people can't avoid it, and something happy may happen to others. The so-called poisonous honey really varies from person to person.