2 English reference Scutellaria barbata and Baicao [Xiangya Medical Dictionary]
Scutellaria barbata [Xiangya Medical Dictionary]
Committee on terminology of traditional Chinese medicine. Terminology of Traditional Chinese Medicine (2004)]
Scutellaria barbata [Chinese medicine terminology Committee]. Terminology of Traditional Chinese Medicine (2004)]
3. Overview Scutellaria barbata is the name of traditional Chinese medicine, which comes from the Journal of Plants and Medicinal Materials in Jiangsu Province [1]. It is the dried whole grass of Scutellaria barbata of Labiatae [2].
Pharmacopoeia of People's Republic of China (PRC) (20 10 edition) records the pharmacopoeia standard of this Chinese medicine.
4 Latin name Scutellaria barbata (La) (terminology of traditional Chinese medicine (2004))
5 English name barbated skullcup herb (Chinese Medicine Terminology (2004))
6 Scutellaria barbata alias: golden ear, common grass, square grass, toothbrush grass [1].
7 Source and place of origin: whole herb of Scutellaria barbata [1]. Jiangsu, Jiangxi, Hubei, Sichuan and other places [1].
8 slightly bitter in taste and cool in nature [1].
9 Functions are indicated for clearing away heat and toxic materials, removing blood stasis, stopping bleeding, inducing diuresis and resisting cancer [1].
1. Treat furuncle and furuncle snake bite [1]. Tamp orally [1].
2. Treat lung abscess, appendicitis, hematemesis, epistaxis, dysentery, stranguria, nephritis edema, hepatitis and ascites due to liver cirrhosis [1].
3. Recently used to treat lung cancer, gastrointestinal cancer and cervical cancer [1]. Decocting: 15 ~ 30g (double fresh) [1].
10 pregnant women should use it with caution [1].
1 1 chemical constituents This product contains baicalin, baicalin, crocin, heterochromatic glycoside, scutellarin, etc. [ 1].
12 pharmacological effects: the crystals extracted by ether have diuretic effect on animals, and baicalein can increase cerebral blood flow and prevent platelet aggregation, which has a good clinical effect on paralysis after cerebrovascular disease [1]. This product also has anti-tumor effect [1].
13 Scutellaria barbata Pharmacopoeia standard 13. 1 is called Scutellaria barbata.
Scutellaria barbata
Scutellaria barbata
13.2 Source This product is the dried whole grass of Scutellaria barbata. Tang, a plant of Labiatae. In summer and autumn, when the stems and leaves are lush, dig, wash and dry.
13.3 characteristics: this product is15 ~ 35cm long, with no hair or sparse coat in floral axis. The roots are very thin. Stems are tufted, thin and square; The surface is dark purple or brownish green. Leaves opposite, with short stems; After flattening, the leaves are mostly wrinkled, triangular, oval or lanceolate, with a length of 1.5 ~ 3 cm and a width of 0.5 ~ 1 cm. Apex obtuse, base broadly cuneate, entire or with some inconspicuous obtuse teeth; The upper surface is dark green and the lower surface is grayish green. Flowers are solitary in the upper axils of stems and branches, and calyx lobes are obtuse and round; Corolla 2-lipped, brownish yellow or light blue purple, about 1.2 cm long, hairy. The fruit is oblate and light brown. Slight breath and bitter taste.
/determination of kloc-0/3.4 13.4./preparation of total flavone reference solution; take a proper amount of breviscapine reference substance, accurately weigh it, and add methanol to make a solution containing 0.2mg per kloc-0/ml.
13.4.2 preparation of standard curve accurately measure 0.4ml, 0.8ml, 1.2ml, 1.6ml and 2.0ml of control solution, put them in 25ml measuring bottles respectively, add methanol to the scale and shake well. With methanol as blank, the absorbance was measured at the wavelength of 335nm by UV-Vis spectrophotometry (Appendix V A), and the standard curve was drawn with absorbance as ordinate and concentration as abscissa.
13.4.3 determination method accurately measure the methanol solution Iml extracted by Soxhlet and diluted to 100ml under [content determination], put it in a 50ml volumetric flask, add methanol to the scale, shake it evenly, prepare according to the standard curve method, determine the absorbance according to law from "taking methanol as a blank", and read the content of breviscapine in the test solution from the standard curve.
In terms of dry products, the total flavonoids in this product shall be counted as Scutellaria baicalensis Georgi (C2 1H 18O 12), and shall not be less than 1.50%.
13.4.4 determination of scutellarin by HPLC (appendix 6 d).
13.4.5 chromatographic conditions and system applicability test with octadecylsilane bonded silica gel as filler; Using methanol-water-acetic acid (35∶6 1∶4) as the mobile phase; The detection wavelength is 335 nm. According to the scutellarin peak, the theoretical plate number should be not less than 1500.
13.4.6 preparation of reference substance solution: take a proper amount of breviscapine reference substance, weigh it accurately, and add the mobile phase to make a solution containing 80μg per 1ml.
13.4.7 Preparation of test solution Take this product powder (pass through No.3 sieve) about 1g, weigh it accurately, put it in Soxhlet extractor, add petroleum ether (60 ~ 90℃) to extract until it is colorless, discard the ether solution, remove the petroleum ether in the residue, add methanol to extract until it is colorless, and transfer it to/kloc-.
13.4.8 determination method Accurately suck the control solution and the test solution 10μl respectively, inject them into the liquid chromatograph, and determine to obtain the product.
The content of scutellarin (C2 1H 18O 12) in this product shall not be less than 0.20%.
13.5 Scutellaria barbata pieces 13.5. 1 Processing to remove impurities, cleaning, cutting into sections and drying.
This product presents irregular fragments. The stem is square and cylindrical, hollow, and the surface is dark purple or brownish green. The leaves are opposite and broken, with dark green upper surface and grayish green lower surface. Calyx lower lip lobes obtuse or rounded; Corolla lip-shaped, brownish yellow or light blue purple, hairy. The fruit is oblate and light brown. Slight breath and bitter taste.
The content determination of 13.5.2 is the same as that of medicinal materials.
13.5.3 Sexual taste and meridian tropism: bitter, bitter and cold. Enter lung, liver and kidney meridians.
13.5.4 Functions: clearing away heat and toxic materials, removing blood stasis and promoting diuresis. Used for furuncle, sore throat, traumatic injury, edema, jaundice and snake bite.
13.5.5 Usage and dosage 15 ~ 30g.
13.5.6 Store in a dry place.
13.6 source: China Pharmacopoeia 20 10.
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