Buffini hydrochloride in English.
3. overview of naoqing: 1. Names of strange points other than meridians; 2. The alias of buprenorphine.
4 The name of the strange point outside the meridian NaoqingNaoqing is the name of the strange point outside the meridian. The Handbook of General New Medical Law was published. It is located at the distal end of the extended leg, at the outer edge of the anterior tibial crest, and 2 inches above the midpoint of the anterior transverse stripes of the ankle joint. Count 2 points from left to right. Indications: drowsiness, dizziness, amnesia, sequelae of polio, foot drop, etc. Usually 0.5 ~ 0.8 inches. [ 1]
Buphening alias, an adrenocortical hormone, Naoqing Buphening is an adrenocortical hormone, which can excite β receptor and has a strong vasodilator effect. Can be used for treating occlusive endarteritis, acrospasm, arteriosclerosis obliterans, hypertensive cerebrovascular diseases, sequelae of cerebral hemorrhage, vasospasm headache, chilblain, cyanosis of hands and feet and peripheral vascular diseases. It is also used for coronary artery insufficiency, coronary arteriosclerosis, inner ear vertigo, other inner ear diseases, central choroiditis, retinitis pigmentosa, etc. The minimum lethal dose is 2g for adults and 200mg for children.
5. 1 Bufening Instructions 5. 1. 1 Drug Name Bufening
5. 1.2 English name Buphenine
5. 1.3 Another name of Naoqing: benzyl propyl phenol amine; Bufuning; Dilot; Clear the brain; Phenoprofen hydrochloride; Alieddin
5. 1.4 classification of drugs in circulatory system >: cardiovascular dilators > direct-acting vasodilators
5. 1.5 dosage form 1. Tablets: 6 mg;
2. Injection: 1 ml: 5mg.
5. 1.6 Pharmacological Effects of Bufening Bufening is an adrenaline-like drug, which mainly excites β-receptors. Its effects of dilating bronchi and exciting the heart are obviously weaker than isoproterenol, and it only retains a strong vasodilator effect. Animal experiments show that the effect of Buphening on increasing peripheral blood flow is mainly caused by directly relaxing arterioles and skeletal muscle microvessels, and it can also dilate cerebral vessels and coronary vessels, which can increase the blood flow of brain and coronary arteries. It can increase the cerebrovascular flow by 32% ~ 43% and the cardiac output by 34%. Buphening can excite myocardium, increase instantaneous blood flow of heart, stabilize arterial blood pressure, have strong effect on capillary bed, reduce capillary tension and promote blood circulation of peripheral blood vessels, thus strengthening metabolism, promoting recovery of injured parts and accelerating growth of new tissues.
5. 1.7 Pharmacokinetics of Bufening; Bufening is well absorbed from gastrointestinal tract after oral administration, and takes effect quickly.
5. 1.8 Buphening is indicated for headache caused by cerebral embolism, cerebral artery infarction and cerebral vasospasm, diffuse encephalopathy caused by hypertension, cerebral sulcus ischemia, cerebral vascular stenosis, migraine, thrombophlebitis, varicose ulcer, chilblain, arteriosclerotic retinopathy, premature delivery and threatened abortion, postoperative placental hemorrhage, and recovery of transplanted tissue after vascular and nerve injury. It has been applied to 7 clinical units 167 patients, such as Union Hospital of China Academy of Medical Sciences, and the curative effect is positive, especially for mild ischemic cerebrovascular disease and central serous retinopathy. Clinical trials show that buprenorphine has the advantages of rapid onset, low toxicity, high safety factor, low dosage and high physiological activity, which is superior to other vasodilators and does not reduce blood pressure and increase heart rate while dilating blood vessels.
5. 1.9 contraindication of acute myocardial infarction with buprenorphine. Acute myocardial infarction is contraindication.
5. 1. 10 note: recent myocardial insufficiency, paroxysmal tachycardia. Use with caution in patients with severe angina pectoris, toxic goiter and digestive tract ulcer.
5. 1. 1 1 Buphening has an adverse reaction similar to papaverine. Such as occasional palpitation, fatigue, dizziness, nausea, vomiting, loss of appetite, blushing and other reactions, but generally will not increase the heart rate.
5. 1. 12 Buphening dosage is 4 ~ 6 mg each time, 3 times a day or as directed by the doctor. Intramuscular injection or intravenous or arterial injection: 2.5mg each time, 1 time/d.
5.2 Bufening Poisoning Bufening (Propafenone, Bufening, Desolotil) is an adrenergic drug, which can excite β receptor and has a strong vasodilator effect. Can be used for treating occlusive endarteritis, acrospasm, arteriosclerosis obliterans, hypertensive cerebrovascular diseases, sequelae of cerebral hemorrhage, vasospasm headache, chilblain, cyanosis of hands and feet and peripheral vascular diseases. It is also used for coronary artery insufficiency, coronary arteriosclerosis, inner ear vertigo, other inner ear diseases, central choroiditis, retinitis pigmentosa, etc. Take orally 3 ~ 6 mg each time, 3 ~ 4 times /d, with a maximum of 12mg each time. Intramuscular injection of 2.5 ~ 5 mg each time, l/d or several times a day. The minimum lethal dose is 2g for adults and 200mg for children. The oral LD50 of mice was 0.25g/kg. [2]
5.2. 1 clinical manifestations [2]
1. Adverse reactions include nausea, vomiting, loss of appetite, palpitation, dizziness, tension and weakness.
2. Poisoning can induce angina pectoris, aggravate myocardial infarction and cause paroxysmal tachycardia; Induce or aggravate hyperthyroidism and peptic ulcer.
5.2.2 The key points for the treatment of butanone poisoning are [2]: