This product comes from dried flower buds or flowers in early flowering period of honeysuckle. Lonicera rubra D. C. Flos lonicerae Or Lonicera pilosa. Collecting and drying flowers before opening in early summer; Or fumigating with sulfur and drying.
English name Lonicera flo
Alias honeysuckle, honeysuckle, Hua Shuang, Erhua, Erbaohua and Egret Flower.
Distribution of origin
Fengqiu county has been certified as the origin of honeysuckle.
Appearance characteristics
Any one may be rod-shaped, thick on the top and thin on the bottom, slightly curved, 2 ~ 3 cm long, with an upper diameter of about 3 mm and a lower diameter of about 1.5 mm, with a yellowish-white or greenish-white surface, which becomes dark and densely pubescent after long storage. Bracts occasionally leaflike. Calyx green, apex 5-lobed, lobes hairy, about 2 mm long. Corolla tubular, apex 2-lipped; Stamens 5, inserted on tube wall, yellow; Pistil 1, ovary glabrous. The smell is fragrant and the taste is light and bitter.
Lonicera japonica is 2.5 ~ 4.5 cm long and 0.8 ~ 2 mm in diameter. The surface is yellowish white to yellowish brown, with no hair or sparse coat. Calyx tube glabrous, apex 5-lobed, lobes triangular and hairy. Open, corolla lower lip inverted. Style glabrous.
Honeysuckle is1.6 ~ 3.5cm long and 0.5 ~ 2mm in diameter. Calyx tube and corolla are densely covered with gray hairs, and ovary is hairy.
Stylosanthes is 2.5 ~ 4cm long and1~ 2.5 ~ 4cm in diameter. The surface is light yellow with purple and hairless. Calyx lobes short triangular. The upper lip of corolla is usually irregular, and the lower part of style is densely villous.
Honeysuckle can also be grown at home. It is a famous garden flower, with beautiful flowers and leaves and evergreen seasons. Suitable for vertical greening materials such as fences, balconies, green corridors, flower stands and trees. , can also be potted. If you arrange some colorful flowers at the same time, the makeup will be light, complement each other and be interesting.
Identification method
Take 0.2g of this product powder, add 5ml of methanol, let stand for 65438±02h, filter, and take the filtrate as the test solution. In addition, chlorogenic acid reference substance was added with methanol to prepare a solution containing 1mg per 1ml as reference substance solution. According to the thin-layer chromatography test (appendix ⅵ b), suck10 ~ 20μ l of test solution and 10μl of reference solution, respectively, onto the same silica gel H thin-layer plate with sodium carboxymethyl cellulose as adhesive, and take out the upper solution of butyl acetate-formic acid-water (7:2.5:2.5) as developing agent. In the chromatogram of the test sample, fluorescent spots with the same color appear in the position corresponding to the chromatogram of the control sample.
Planting technique
First, variety selection
Honeysuckle, also known as honeysuckle and honeysuckle, is commonly known as Hanako locally. There are three major strains of honeysuckle in Pingyi: chicken feet flower, hairy flower and honeysuckle.
1. Chicken-claw flower: The flower buds are clustered at the top of the flower branches in a chicken-claw shape, which is divided into big chicken-claw flower and small chicken-claw flower. They like fat and water, bloom early and have good production performance. The bud is thin and slightly shorter, and the color is lighter, which is the first choice for processing.
2. Big hairy flower: vigorous growth, big and loose pier shape, long and thick branches, long buds, developed roots, drought resistance and barren resistance, suitable for planting in thin mountainous areas, terraces and weirs.
3. honeysuckle. It is the original wild species of honeysuckle. The leaves are long, the buds are thin, with purple stripes, and the processing quality is excellent.
Second, raise seedlings.
1, layering planting method: select healthy branches that are one or two years old in flood season, cut them into 30 cm sections, remove the lower leaves, and plant them in all holes, cover them with soil and compact them. If the water content is insufficient, water is needed, and the survival rate is over 90%.
2, cuttage seedling: when pruning honeysuckle, cuttage is carried out at the cutting branch of 20 cm. Border cutting, row spacing 20 cm, plant spacing 2 cm. It can be cut in spring, summer and autumn, and can be transplanted after 100 days.
Third, planting
Honeysuckle is mainly planted on hillsides, dams, ditches and roadsides, mostly scattered. With the improvement of planting level, the close planting garden of honeysuckle gradually developed.
Planting time is mostly in February in spring, digging a pit 0.5 meters square and watering the soles of feet. The base fertilizer is mainly organic fertilizer, and 3-5 plants are planted in each hole. After planting, cover the soil and compact. The planting spacing of the close planting garden is 1× 1. 3 meters, planting about 500 piers per mu.
Fourth, growth management
1, fertilization
Generally, organic fertilizer is applied as base fertilizer before winter. During the growth period, according to the growth status of Lonicera japonica Thunb, topdressing is carried out in stages for 3-5 times, with topdressing of organic fertilizer 15-20kg or ternary compound fertilizer of 0.5kg pier each time. Honeysuckle generally does not need watering during the growth period. In case of severe drought, water should be used to fight drought.
2, reasonable pruning
Mostly before winter or early spring. It is necessary to prune the weak diseased branches to promote the development of new branches, and at the same time, combine pruning to raise honeysuckle seedlings.
3, pest control
The main pests of honeysuckle. There are: honeysuckle inchworm. Aphid. Woodpeckers, etc. Use 40% dimethoate EC 100- 125g mixed with 50% dichlorvos EC 150-200g mixed with 40-200g water for control.
Verb (abbreviation for verb) harvest
The flowering period of honeysuckle usually lasts from late May to mid-June, 10, about 150 days. The first crop is in late May, the second crop is in the middle and late July, the third crop is in the middle of August, and the fourth crop is in the middle of 10. The flowering period of each crop is about 7 days.
When the upper part of the bud is white, early harvest will affect the yield and late harvest will reduce the quality.
honeysuckle flower extract
Honeysuckle extract English name: HoneySuchle Flowers Extract
The main components of honeysuckle extract: chlorogenic acid 98%, 99%.
Detection method: high performance liquid chromatography.
CAS number: 327-97-9
Description: white fine powder
Note: High-purity chlorogenic acid can be used as pharmaceutical raw material for powder injection, injection and injection.
Solubility: Good water solubility. Soluble in hot water, ethanol and acetone, completely soluble. Very slightly soluble in ethyl acetate.
Molecular formula and molecular weight: C 16H 18O9=354.30.
EINECS login number: 206-325-6
Melting point 205-209°C Specific curl: -36 (C = 1, H2O).
Honeysuckle extract-high purity chlorogenic acid Manufacturer: Aite Natural Products1387 5855783 www.ataherb.com.
Medicinal value
The flower buds of honeysuckle belong to many plants and are used as honeysuckle in different areas. Except honeysuckle. Red honeysuckle. Honeysuckle. And honeysuckle. And honeysuckle. Honeysuckle. Honeysuckle. Lonicera breviglandularis Honeysuckle. Penny II and honeysuckle. Miq。 L.macrathoides hand -Mazz，L.buchananii Lacein kew Ball，L.rhytidophylla Hand。 -Maz, Simis hymes. Lonicera flavescens L.tatarica Linn.var.tatarica, L.crassifolia, etc.
Honeysuckle is the bud and the first flower of Lonicera japonica, a perennial semi-evergreen woody vine of Caprifoliaceae. Honeysuckle is sweet and cold, and has the functions of clearing away heat and toxic materials and dispersing wind and heat. The general dosage is 6 ~ 15g, which can be decocted in water or taken in pills. Do not use it for people with spleen and stomach weakness and qi deficiency. We ancient people found that honeysuckle can detoxify bacteria. In the Song Dynasty, Zhang Bangji's "Mo Zhuang Man Lu" recorded such a story: during the Chongning period, several monks from Baiyun Temple in Tianping Mountain, Pingjiang Prefecture collected a basket of wild mushrooms from the mountain to cook food. Unexpectedly, wild mushrooms were poisonous, and the monk began to vomit and diarrhea after a full meal. Three of the monks were safe and sound because they took fresh honeysuckle in time, while all the other monks who didn't take honeysuckle in time died in vain. It can be seen that the detoxification effect of honeysuckle is extraordinary.
Patent prescription Liuwei Flavone Tea: Chinese herbal medicine is drunk by drinking tea. This tea is composed of six kinds of Chinese herbal medicines with the same origin of medicine and food, such as honeysuckle, ginkgo biloba, cassia seed, Sophora japonica, hawthorn and chrysanthemum, which are stipulated by the Ministry of Health, and mainly contains plant flavonoids that cannot be synthesized by human body. The raw materials are carefully selected, processed and processed into teabags, so it is called "Six Flavonoids Tea". This is no ordinary tea, and it contains no tea ingredients. It is a Chinese herbal medicine, which is drunk by drinking tea. Liuwei Flavone Tea is not a health care product, but a functional food (batch number: Shanwei Food Certificate No. ) is a functional food with drug effect.
Content determination
According to high performance liquid chromatography (appendix ⅵ d).
Octadecylsilane bonded silica gel is used as a filler for chromatographic conditions and system suitability test. Acetonitrile -0.4% phosphoric acid solution (13: 87) as mobile phase; The detection wavelength is 327nm. The theoretical plate number is not less than 1000 calculated by chlorogenic acid peak.
Preparation of Reference Solution Accurately weigh the appropriate amount of chlorogenic acid reference substance, put it in a brown volumetric flask, and add 50% methanol to make a solution containing 4μg per 1ml, which is obtained (stored below 10℃).
Preparation of test solution Take about 0.5g of this product powder, weigh it accurately, put it in a conical flask with a stopper, add 50ml 50% 50% methanol accurately, weigh it, perform ultrasonic treatment for 30min, let it cool, weigh it again, make up the weightlessness with 50% methanol, shake it evenly, filter it, accurately measure 5ml of continuous filtrate, put it in a 25ml brown volumetric flask, and add 50% methanol to the scale.
The determination method accurately absorbs 5 ~ 10μ l of the control solution and the test solution, and injects them into the liquid chromatograph for determination.
This product contains chlorogenic acid (C 16H 18O9) not less than 1.5%.
Sexual taste orientation
Sweet and cold. Enter lung, heart and stomach meridians.
Functional indication
Clearing away heat and toxic materials, cooling wind and heat. Used for carbuncle, furuncle, laryngitis, erysipelas, bloody dysentery, wind-heat cold, fever and fever.
dosage
6~ 15g .
Storage method
Store in a cool and dry place, moisture-proof and moth-proof.
Chinese medicine believes that honeysuckle is cold in nature, sweet in taste, flat in qi, and has the effect of clearing away heat and toxic materials, and can be used to treat toxic heat, swelling and carbuncle. Because it has the function of dispelling pathogenic factors, it can also treat exogenous wind-heat and febrile diseases. For example, Yinqiao Jiedu tablets (pills) for the treatment of wind-heat colds take honeysuckle as the main medicine. Yinhuang tablets made from Scutellaria baicalensis Georgi can treat acute upper respiratory tract infection, acute pharyngitis and acute tonsillitis. Flos Lonicerae can be distilled with water to obtain "Flos Lonicerae Dew", which has the function of clearing away heat and relieving summer heat, and can be used to treat children's heat furuncle, miliaria and summer heat.
Since ancient times, there has been such a custom among Chinese people. The hot summer is coming. Drinking honeysuckle tea for children several times can prevent the occurrence of hot furuncle in summer. In hot summer, drinking honeysuckle tea can prevent heatstroke, enteritis, dysentery and other diseases.
In hot summer, people are prone to heatstroke. Herbal tea made of honeysuckle can prevent heatstroke if you drink it regularly. From late summer to Mid-Autumn Festival, bacillary dysentery and enteritis are frequent. Honeysuckle can be used as the main medicine, and Coptidis Rhizoma and Scutellariae Radix can be decocted into decoction for oral administration, which has a good preventive and therapeutic effect. Honeysuckle is in bud, yellow and white in color, and it is better to pick it when it is fat. If you pinch a pinch of high-quality honeysuckle, put it in a glass and pour boiling water, after a while, you will see the flower buds hanging vertically in the water, not floating or sinking, and graceful. After water soaked the bud, it sank to the bottom of the cup.
According to pharmaceutical chemical analysis, honeysuckle contains luteolin, inositol, saponin, tannin and so on. Pharmacological experiments show that honeysuckle has a wide antibacterial spectrum, and has inhibitory effects on Shigella dysenteriae, typhoid bacillus, Escherichia coli, pertussis bacillus, diphtheria bacillus, Pseudomonas aeruginosa, tuberculosis bacillus, staphylococcus, streptococcus and pneumococcus. And anti-influenza virus. Clinically, it is also used to treat infections caused by the above pathogenic microorganisms.
Recent studies have pointed out that honeysuckle can promote lymphocyte transformation, and lymphocyte transformation rate can reflect cellular immune function, that is, improve organism immunity. Honeysuckle can also enhance the phagocytosis of white blood cells and improve immune function from another angle. Honeysuckle can also promote the release of adrenocortical hormone, and has obvious inhibitory effect on acute inflammation.
Animal experiments by Nanjing Institute of Wild Plants have proved that honeysuckle can significantly improve the tolerance of animals to high temperature environment. When 50% of the animals in the control group died of high temperature, only 6% of the animals fed with honeysuckle tea died in the same environment. It is proved that honeysuckle has the effect of clearing away heat and relieving summer heat.
Yinju drink made of honeysuckle and chrysanthemum was used as tea to treat 200 cases of hypertension and arteriosclerosis, and the effect was good. Among them, 46 cases were systematically observed, 35 cases had their blood pressure reduced to normal, and the rest also decreased to varying degrees, which could improve symptoms such as dizziness, headache and insomnia. The curative effect of honeysuckle injection on acute tonsillitis is not inferior to that of antibiotics, and no toxic or side effects are found during the treatment.
Pharmacology of honeysuckle
Honeysuckle contains cyclohexanol, flavonoids, inositol, saponins and tannins. It has broad-spectrum antibacterial effect, has strong inhibitory effect on various pathogenic bacteria such as Staphylococcus aureus and Shigella dysenteriae, and also has inhibitory effect on various pathogenic microorganisms such as leptospira, influenza virus and pathogenic mold. In addition, honeysuckle also has obvious anti-inflammatory and antipyretic effects, and the water and wine extracts of honeysuckle have obvious killing effect on experimental tumor cells.
The distillate obtained by distilling the flowers and leaves of honeysuckle is called honeysuckle dew. Eating in summer is not only sweet and delicious, but also has a good effect of clearing away heat and relieving summer heat. There used to be a porcelain jar with honeysuckle dew on the counter of the pharmacy. In the past, when the variety of drinks was extremely scarce, the blue and white porcelain altar on the counter made many children's eyes itch.
In the process of Zhuge Liang's capture of Meng Huo, most soldiers were acclimatized and suffered from miasma in Shan Lan. After passing through a small village, Zhuge Liang felt pity and distributed rations to help when he saw the villagers were yellow, hungry and thin. The villagers are very grateful. When a white-haired old man who was born and raised learned that many Shu soldiers were suffering from "heat poisoning", he called his twin granddaughters: "Jinhua and Yin Hua, go and collect some baskets of fairy medicine to solve problems for the Shu army." However, three days later, the sisters still didn't come back. People look for it in many ways. On a cliff, I saw two medicine baskets full of herbs, next to which were the footprints of wild wolves and torn clothes and shoes. ...
Shu soldiers were saved by eating herbs, but Jinhua and Yinhua gave their lives for it. In memory of them, people call the flower of this herb "honeysuckle".
Honeysuckle. Herbs are worth ten thousand gold.
Honeysuckle, also known as honeysuckle, golden flower, honeysuckle, rattan flower, etc. Every summer and autumn, this vine climber is found in the mountains and hills of northern and southern provinces of China, with yellow and white flowers and fragrant smell. This is "honeysuckle". When the flowers bloom, they are pure white at first, and then turn yellow, which is very beautiful. The collection of this kind of flower is very particular. It must be picked in the early morning when the dew is just dry, dried in the sun or dried in the shade in time, so that the efficacy is good.
According to relevant literature, honeysuckle has been planted in China for more than 2200 years. As early as the Qin and Han dynasties, there was a record of honeysuckle in Shennong Herbal Classic, which was called "Lingdong never dies". Duan, a poet in the Jin Dynasty, said: "There are vines, herons and vines, which are naturally inhuman. There are silvery white stamens in the golden flower, and the green color is unique.
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Functional indication
Compendium of Materia Medica states that honeysuckle is good at detoxifying, so it can cure carbuncle, swollen poison, sores and tinea. Honeysuckle has been used to clear away heat and toxic materials since ancient times, to treat fever, dysentery with toxic blood, carbuncle and swelling, and also to treat wind-heat cold and bronchitis.
Modern pharmacological research shows that honeysuckle has antibacterial, antiviral, anti-inflammatory, antipyretic and immunomodulatory effects.
Bian Xiao recommended: Good wine in midsummer: honeysuckle.
Common prescription
Prescriptions and medicated diets containing honeysuckle are especially common. According to the survey, honeysuckle is used in13 of traditional Chinese medicine prescriptions in China.
Heat-toxic carbuncle can be taken orally with concentrated decoction alone, or combined with dandelion, viola yedoensis and chrysanthemum indicum to enhance the efficacy of clearing away heat and toxic materials and reducing swelling. The representative party has a five-flavored disinfectant drink, which comes from the key prescription of surgical psychology in Medical Zong Jin Jian: "honeysuckle San Qian, wild chrysanthemum, dandelion, viola yedoensis and cabbage are decocted for eight minutes, and half a cup of ashless wine is added, and then boiled for two or three times. Fry it again and you will sweat. " Has the functions of clearing away heat and toxic materials and eliminating furuncle. Indications: all kinds of furuncle, furuncle and furuncle swelling, local swelling and heat pain, or fever and aversion to cold, red tongue with yellow fur and rapid pulse.
Although there are only five kinds of this prescription, it is the first choice of traditional Chinese medicine to treat carbuncle, sore and furuncle caused by accumulation of fire poison. The modern dosage and decoction method are: honeysuckle 20g, wild chrysanthemum 15g, dandelion, viola yedoensis and Chinese cabbage. After decocting in water, add a proper amount of kimono, and mash the residue and apply it to the affected area.
For those who have swollen and toxic sores for the first time, or those who have suppurated but not festered, they can be combined with pangolin, spina gleditsiae, shellfish and angelica dahurica. The representative prescription is Xianfang Huoxue Drink, which comes from the Good Prescription for Women: "Pangolin, Glycyrrhiza uralensis Fisch, Saposhnikovia divaricata, Myrrha, Radix Paeoniae Rubra, Radix Angelicae Sinensis, Olibanum, Fritillaria, Trichosanthes Radix, Acanthopanax Senticosus, Radix Angelicae Dahuricae, and Flos Lonicerae are decocted in three bowls of good wine to a bowl and a half. If the upper body is finished; If you are in the lower body, take it before eating, and add three or four cups of alcohol to help the medicine. " Xianfang Huoxue Decoction is mainly used for clearing away heat and toxic materials, promoting blood circulation and qi circulation, and reducing swelling and ulceration. Known as "the holy medicine for sores and carbuncles, the first side of surgery", it is used for all sores and itching. Honeysuckle is good at clearing away heat and toxic materials. Radix Angelicae Dahuricae and Radix Saposhnikoviae are used to dispel pathogenic factors and completely solve the heat toxin from the outside. Pollen and Fritillaria clear away heat, resolve phlegm, disperse nodules and eliminate carbuncle.
Modern dosage: 3 grams of pangolin, 3 grams of spina gleditsiae, 3 grams of angelica tail, 3 grams of licorice, 9 grams of honeysuckle, 3 grams of radix paeoniae rubra, 3 grams of frankincense, 3 grams of myrrh, 3 grams of trichosanthis radix, 9 grams of dried tangerine peel, 3 grams of radix Saposhnikoviae, 3 grams of Fritillaria and 3 grams of angelica dahurica.
Application value
Honeysuckle is widely used. In recent years, honeysuckle has been used in many traditional Chinese medicine prescriptions for preventing and treating SARS. In daily life, people often use honeysuckle to soak in water instead of tea to treat sore throat and prevent upper respiratory tract infection. The method is: take 20 grams of honeysuckle and decoct it in water instead of tea or make tea, daily 1 dose. In addition, many inflammatory diseases are also treated with honeysuckle.
(1) is used for the initial onset of exogenous wind-heat or epidemic febrile disease. Honeysuckle. Sweet and cold in nature, it not only clears qi and divides heat, but also clears blood and divides heat. In addition, this product can clear away heat and dispel cold, and can be used for patients with exogenous wind-heat or fever with different exterior and interior, and excessive internal heat. It is often used with Forsythia suspensa, Arctium lappa and Mint.
(2) For sore and sore throat. Honeysuckle has a strong effect of clearing away heat and toxic materials and is often used in surgery. Generally used for sore, carbuncle, swelling and pain. It is more suitable for diseases that belong to "yang syndrome" in syndrome differentiation. It can be taken orally with Taraxacum mongolicum, Viola yedoensis, Forsythia suspensa, Cortex Moutan and Radix Paeoniae Rubra, or mashed by fresh people for external application.
(3) For diarrhea and hematochezia caused by heat toxin (mucus and blood in feces). Heat toxin accumulates in the intestine, which causes diarrhea and bloody stool when it enters the blood. Honeysuckle. It can cool serum and detoxify heat, so it treats bloody dysentery and bloody stool. Honeysuckle is commonly used to stir-fry charcoal in clinic. , Coptidis Rhizoma, Radix Paeoniae Alba and Portulaca oleracea.
(4) Honeysuckle tastes sweet and cold and smells fragrant. It can clear exterior, clear heat and detoxify, which is especially important for treating positive ulcers. Adding Fructus Forsythiae, Fructus Arctii, Herba Menthae and Herba Schizonepetae to relieve exterior heat; Use fresh rehmannia root, Scrophularia root, forsythia suspensa, bamboo leaves, etc. It can clear the camp and release heat; With viola yedoensis, wild chrysanthemum and dandelion, it can detoxify and treat sores; Astragalus membranaceus, Angelica sinensis and Glycyrrhiza uralensis can relieve carbuncle swelling. Radix Scutellariae, Radix Paeoniae Alba, Radix Glycyrrhizae, etc. , can clear away heat and stop dysentery.
★ Take Flos Lonicerae 15g and Radix Glycyrrhizae 3g, decoct and take orally to treat pharyngitis.
★ Take 60 grams of honeysuckle and 20 grams of hawthorn and take it instead of tea, which can cure cold, fever, headache and sore throat.
★ Take honeysuckle, dandelion 25g, licorice 15g, daily 1 dose, and decoct with water to treat parotitis.
★ Take 9 grams of Flos Lonicerae, Fructus Forsythiae, Radix Isatidis, Rhizoma Phragmitis, and Radix Glycyrrhizae, and decoct them in water, daily 1 dose, for 3 ~ 5 days, which can prevent meningitis.
★ Take honeysuckle10g, chrysanthemum10g, honey10g, add appropriate amount of water, decoct for 30min, and filter out the decoction for drinking, which can cure summer heat, headache, upset and thirst.
★ Take appropriate amount of fresh stems, leaves and flowers of honeysuckle, wash them with cold boiled water, chew them carefully and swallow them, which can cure mushroom poisoning.
★ Take honeysuckle 15g, bake and grind into powder, and mix with water to treat dysentery.
★ Take 300g of Flos Lonicerae, 90g of Rhizoma Coptidis and 90g of Scutellariae Radix, decoct with water, and take 30 ml of liquid medicine 1000 ml, four times a day, which can cure acute bacillary dysentery.
★ Take 24g of honeysuckle, 0g of dandelion15g, 9g of forsythia suspensa, 9g of dried tangerine peel, 6g of green tangerine peel and 6g of licorice, and decoct with water every day, which can cure early acute mastitis.
★ Take Flos Lonicerae, Flos Chrysanthemi Indici, Herba Taraxaci, Herba Violae 65438±05g, and Herba Solani Tuberosi 6g, with 65438 0 doses per day, and decoct with water to treat carbuncle, swelling and sore.
★ Take 60 ~ 90g of honeysuckle, 30 ~ 60g of dandelion and 9 ~ 15g of liquorice, once a day 1 dose, and decoct with water, which can be used for the adjuvant treatment of acute simple appendicitis.
★ Take honeysuckle 15g, plantain 30g, Eclipta prostrata 30g, motherwort 30g, once a day 1 dose, and decoct with water to treat urinary tract infection.