The main contraindications for drug use include the following aspects:
1. Incompatibility: In compound compatibility, some drugs should be avoided from being used together. "Shen Nong's Materia Medica" calls the relationship between these drugs "inimical" and "opposite." According to the statistics of "Shu Materia Medica", there are 60 kinds of medicines recorded in "Ben Jing" that are antagonistic to each other and 18 kinds of opposites. The understanding and development of compatibility taboos in the past dynasties are inconsistent in ancient books. During the Jin and Yuan Dynasties, they were summarized as "Eighteen Rebels" and "Nineteen Fears" and compiled into songs. The contents of the songs are listed below.
(1) Eighteen antis: The Materia Medica clearly states that the eighteen antis include algae, halberd and coriander, which all fight against grass, half-capry and coriander against black grass, and various ginseng, pungent peony and hellebore.
(2) Nineteen Fears: Sulfur is the essence of fire, and saltpeter will fight at the sight; mercury should not be seen with arsenic; wolfsbane is the most afraid of the Mi Tuo monk; Croton is the most ferocious and partial to Morning glory is unfavorable; lilacs should not be seen with turmeric; tooth salt cannot be combined with Beijing's triangular ribs; Sichuan Wu and Cao Wu are not suitable for rhinoceros; ginseng is most afraid of Wulingzhi; Guangui is good at regulating air-conditioning, and it will be compatible with stone fat. bully.
However, the concept of "nineteen fears" has different meanings from "xiangwei", one of the "seven emotions" in "Shen Nong's Materia Medica Preface".
Some of the "Nineteen Fears" and "Eighteen Antis" medicines are somewhat different from their actual applications. Doctors in the past have also discussed them and quoted ancient prescriptions as evidence to prove that some medicines can still be used together. For example, Gansui Banxia Decoction uses licorice and Gansui together; Shixiang Soul-Reviving Pill uses cloves and turmeric together; Dahuoluo Dan uses Aconitum and rhinoceros horn together, etc. Since further research is needed on the "19th fear" and the "18th rebellion", a cautious attitude should be adopted at present. Generally speaking, for some of these drugs, blind combined use must be avoided without sufficient basis and application experience.
2. Contraindications for use in pregnancy: Some drugs have side effects of damaging the fetus and causing abortion, so they should be contraindicated in pregnancy. According to the different degree of damage to fetal cells, drugs can generally be divided into two categories: prohibited and used with caution. Most of the drugs that are prohibited are highly toxic or have strong medicinal properties, such as croton, morning glory, spurge, cantharides, pokeweed, musk, trigonatum, zedoary, leech, horsefly, etc.; those that should be used with caution include stimulating menstruation and removing blood stasis, Drugs for promoting qi and breaking stagnation, as well as pungent heat, such as peach kernel, safflower, rhubarb, citrus aurantium, aconite, dried ginger, cinnamon, etc. Any prohibited drugs must not be used; drugs that should be used with caution can be used according to the condition of pregnant women. However, when there is no special necessity, it should be avoided as much as possible to prevent accidents.
3. Dietary taboos when taking medicine: Dietary taboos are referred to as taboos, which are commonly referred to as taboos. In ancient literature, it is recorded that Changshan avoids green onions; Rehmannia glutinosa, Polygonum multiflorum avoids onions, garlic, radish, mint and turtle meat; Poria and vinegar are avoided; Turtle shells avoid amaranth, and raw green onions are avoided in honey. This means that certain foods should not be eaten while taking certain medicines. In addition, due to the disease, during the medication period, any food that is difficult to digest and has special irritation, such as cold, sticky, fishy smell, etc., should be avoided as needed. Patients with high fever should also avoid oil.