Shennong's Classic of Materia Medica, also known as Classic of Materia Medica or Classic of Materia Medica, was written in the Han Dynasty under the pseudonym Shennong. It is one of the four classic works of traditional Chinese medicine and the earliest known works of traditional Chinese medicine. Shennong's Classic of Materia Medica is divided into three volumes, containing 365 kinds of drugs. It is divided into three categories: upper, middle and lower, and its conciseness has become the essence of Chinese medicine theory. Shennong Herbal Classic records the curative effects of 365 kinds of drugs, most of which are true and reliable, and are still commonly used in clinic. It puts forward the idea of dialectical medication. The indications of drugs can reach 170, and there are specific regulations on dosage and time, which also lays the foundation for Chinese medicine. Legend originated from Shennong and was handed down from generation to generation. It was compiled into a book in the Eastern Han Dynasty. The book was not written in a moment, and the author was not alone. Many medical scientists in Qin and Han dynasties collected, summarized and sorted out the monographs on pharmaceutical experience at that time, which was the first book in China to systematically summarize traditional Chinese medicine. Most prescription theories and compatibility laws of traditional Chinese medicine and the principle of "harmony of seven emotions" have played a great role in the practice of medication for thousands of years and are the source of the development of TCM theory.