According to the prescription of traditional Chinese medicine, this prescription is often used for rheumatic diseases such as rheumatoid arthritis and rheumatoid arthritis. Then, let's see if we can find out the evil of rheumatism from the discussion of rheumatism in western medicine.
According to the research of modern medicine, rheumatoid arthritis is an allergic disease, which is mostly caused by group A streptococcus. At present, it is believed that the pathogenesis is that the M protein on the cell wall of Streptococcus forms an immune complex with the corresponding antibody, which is deposited on the synovium of joints, causing inflammatory reaction and tissue damage characterized by congestion and edema, local necrosis and neutrophil infiltration. Rheumatoid arthritis also belongs to immune complex hypersensitivity. The immune complex formed by rheumatoid factor and denatured immunoglobulin G is repeatedly deposited on the synovium of facet joints all over the body, resulting in swelling, deformation and stiffness of facet joints and loss of motor function.
At present, it is believed that rheumatoid arthritis is related to the infection of group A hemolytic streptococcus, and the main mechanism of its pathogenesis is the autoimmune reaction induced by streptococcus. Rheumatoid arthritis may be related to many pathogens. Cold, dampness, fatigue, malnutrition, trauma and mental stimulation can also induce this disease, leading to immune disorder. Therefore, the main methods to treat rheumatoid arthritis and rheumatoid arthritis are sterilization and anti-inflammation.
Comparing the two expressions, does the evil of rheumatism refer to germs? Let's continue to analyze the efficacy of the main components in Notopterygium Shi Sheng Decoction.
Notopterygium root, as the principal drug in the prescription, has obvious anti-inflammatory effect and can inhibit the abnormal secretion of pro-inflammatory cytokines. Radix Angelicae Pubescentis can significantly reduce the swelling degree of the body, and both of them have clear anti-inflammatory effects, which is consistent with the traditional Chinese medicine saying that dispersing rheumatism in the whole body and dredging joints to stop arthralgia. Anti-inflammation is closely related to dispelling wind and overcoming dampness. As an official medicine, Saposhnikovia divaricata has inhibitory effect on delayed hypersensitivity and antibacterial effect on Streptococcus hemolyticus B. Ligusticum can significantly inhibit swelling and reduce the expression of pro-inflammatory cytokines, and sterilization and anti-inflammation should be synonymous with dispelling wind and overcoming dampness. Adjuvant drugs Chuanxiong and Vitex negundo have the effects of regulating blood coagulation and analgesia, and also have a soothing effect on the deposition of immune complex.
Through the comparative analysis of Qianghuo Shi Sheng Decoction in Chinese and Western medicine, it can be clearly seen that the evil of rheumatism mentioned in Chinese medicine probably refers to bacterial infection, while expelling wind in the treatment method is related to antibacterial, and overcoming dampness is related to anti-inflammation.