2 English reference to the fruit of Chinese wolf berries [2 1 century English-Chinese-English bilingual dictionary]
A Lycium barbarum [2 1 Century English-Chinese-English Bidirectional Dictionary]
Lycium barbarum [Landau Chinese-English Dictionary]
Lycium barbarum L. [Xiangya Medical Dictionary]
Lycium barbarum, fruit [Xiangya Medical Dictionary]
Lycium barbarum L. [Xiangya Medical Dictionary]
Committee on terminology of traditional Chinese medicine. Terminology of Traditional Chinese Medicine (2004)]
Committee on terminology of traditional Chinese medicine. Terminology of Traditional Chinese Medicine (2004)]
3. Summarize Lycium barbarum as the name of traditional Chinese medicine and publish a medical record. It is the dried and mature fruit of Lycium barbarum L. in Solanaceae [1].
Pharmacopoeia of People's Republic of China (PRC) (20 10 edition) records the pharmacopoeia standard of this Chinese medicine.
4 Latin scientific name Lycium barbarum L. (Chinese medicine terminology (2004))
5 English name Lycium barbarum (Chinese medicine terminology (2004))
The aliases of Lycium barbarum are Lycium barbarum and Lycium barbarum. ..
7 source Lycium barbarum is the fruit of Lycium barbarum in Ningxia of Solanaceae [2].
8 Origin Lycium barbarum is mainly produced in Ningxia, Gansu and Hebei [2].
9 sexual taste is sweet and flat; Into the liver and kidney meridian [2].
10 Lycium barbarum has the effects of tonifying kidney, replenishing essence, nourishing liver and improving eyesight, and can be used to treat yin deficiency of liver and kidney, soreness of waist and knees, dizziness, thirst and nocturnal emission [2].
Lycium barbarum is a commonly used blood-enriching drug in ophthalmology, which has the effects of nourishing yin and blood, nourishing liver and kidney, and benefiting shrewdness: it is used for blurred vision, flying mosquitoes and flies, green blindness, cold tears and so on caused by liver and kidney loss and essence blood failing to benefit eyes. This crystal is a good medicine for nourishing liver and kidney and benefiting eyesight, and is suitable for various syndromes of liver and kidney yin deficiency. It is often combined with Radix Rehmanniae Preparata, Cornus officinalis and Chrysanthemum, such as Qiju Dihuang Pill.
1 1 Lycium barbarum soup Usage and dosage: 6 ~ 12g [2].
12 chemical constituents of Lycium barbarum The fruit of Lycium barbarum in Ningxia contains betaine, Lycium barbarum polysaccharide, Lycium barbarum glycoprotein, scopolamine, vitamins and amino acids [2].
13 pharmacological effects of Lycium barbarum water extract and Lycium barbarum polysaccharide enhance the immune function of the body and prevent leukopenia caused by cyclophosphamide.
The aqueous extract of Lycium barbarum has a certain protective effect on liver injury induced by carbon tetrachloride in mice and rats, and has a hypolipidemic effect [2].
The water extract of Lycium barbarum can cause cholinergic effects such as heart inhibition, blood pressure decrease and intestinal smooth muscle contraction in rabbits [2].
Lycium barbarum also has hypoglycemic effect [2].
Lycium barbarum can also reduce blood lipid, resist oxidation and resist tumor [2].
14 Chinese wolfberry pharmacopoeia standard 14. 1 is called Lycium barbarum L.
medlar
Chinese wolfberry
14.2 Source This product is the dried and mature fruit of Lycium barbarum L. in Solanaceae. Harvest the fruits when they are red in summer and autumn, dry them with hot air, or dry them until the skin is wrinkled and the fruit stalks are removed.
14.3 properties this product is spindle-shaped or oval, with a length of 6 ~ 20mm and a diameter of 3 ~ 10mm. The surface is red or dark red, with small protruding style marks at the top and white fruit stalk marks at the base. The pericarp is flexible and shriveled; The flesh is soft. 20 ~ 50 seeds, kidney-shaped, flat and upturned, long 1.5 ~ 1.9 mm, wide 1 ~ 1.7 mm, with light yellow or brownish yellow surface. Slight breath, sweet taste.
14.4 Identification (1) The powder of this product is yellow orange or reddish brown. The surface of epicarp epidermal cells is polygonal or long polygon, the longitudinal wall is flat or wavy, and the outer flat wall has parallel horny stripes. The parenchyma cells of mesocarp are polygonal with thin walls, and there are orange-red or reddish-brown spherical particles in the cell cavity. The surface of seed coat stone cells is irregular polygon, with thick wall, wavy bending and clear bedding.
(2) Take 0.5g of this product, add 35ml of water, boil it for 65438±05min, let it cool, filter it, shake the filtrate with 65438 0.5ml of ethyl acetate, separate out the ethyl acetate solution, and concentrate it to 65438±0ml as the test solution. In addition, 0.5g of Lycium barbarum was taken as the control medicinal material, and the control medicinal material solution was prepared by the same method. According to the thin-layer chromatography (Appendix VIB) test, absorb 5ul of the above two solutions, spot them on the same silica gel G thin-layer plate, and use ethyl acetate chloroform formic acid (3: 2: 1) as the developing agent. Unfold, taking out, air dry, and inspecting under ultraviolet light (365nm). In the chromatogram of the test sample, fluorescent spots with the same color appear at the positions corresponding to the chromatogram of the control medicinal materials.
14.5 Check that the moisture content of 14.5. 1 shall not exceed 13.0% (appendix ⅸ H first method, temperature 80℃).
14.5.2 the total ash content shall not exceed 5.0% (appendix ⅸ k).
14.5.3 heavy metals and harmful elements shall be determined by the determination method of lead, cadmium, arsenic, mercury and copper (appendix ⅸ B atomic absorption spectrophotometry or inductively coupled plasma mass spectrometry), and the lead shall not exceed 5 parts per million; Cadmium shall not exceed three parts per million; Arsenic shall not exceed two parts per million; The mercury content shall not exceed two parts per million; The copper content shall not exceed 20 parts per million.
14.6 for the hot-dip method under the water-soluble extract determination method (appendix X A), the extract content shall not be less than 55.0%.
14.7 content determination14.7./preparation of Lycium barbarum polysaccharide reference solution take 25mg of anhydrous glucose reference, weigh it accurately, put it in a 250ml volumetric flask, add a proper amount of water to dissolve it, dilute it to scale, and shake it evenly to get the final product (0./kloc-0 per ml)
Preparation of standard curve? Accurately measure 0.2ml, 0.4ml, 0.6ml, 0.8ml and 1.0ml of control solutions, put them in a test tube with a plug, add water to 2.0ml respectively, add1ml of 5% phenol solution to each part accurately, shake well, quickly and accurately add 5ml of sulfuric acid, shake well, and let stand10. With the corresponding reagent as blank, the absorbance is measured at the wavelength of 490nm according to the ultraviolet-visible spectrophotometry (Appendix V A), and the standard curve is drawn with absorbance as the ordinate and concentration as the abscissa.
Determination? Take about 0.5g of coarse powder of this product, accurately weigh it, and add 100ml of ether. Heating reflux 1 hour, standing, cooling, carefully discarding the ether solution, and putting the residue in a water bath to volatilize the ether completely. Add 1 00 ml of 80% ethanol, heat reflux1hour, filter while it is hot, wash the filter residue with 30ml of hot 80% ethanol and filter it several times, put the filter residue and filter paper in a flask, add 150ml of water, and heat reflux for 2 hours. Filter while it is hot, wash the filter with a small amount of hot water, combine the filtrate and washing liquid, let it cool, move it to a 250ml volumetric flask, dilute it with water to scale, shake it evenly, accurately measure 65438±0ml, put it in a test tube with a plug, add 65438 0.0 ml of water, and add 65438 0.0 ml of 5% phenol solution accurately according to the method under the standard curve preparation.
In terms of dry products, the content of Lycium barbarum polysaccharide should be no less than 1.8% in terms of glucose (C6H 12O6).
14.7.2 betaine Chop this product, take about 2g, weigh it accurately, add 50ml of 80% methanol, heat and reflux it 1 hour, let it cool, filter it, wash the residue with 80% methanol: 30m 1 and filter it several times, combine the washing liquid and filtrate, and concentrate it to/kloc-. Filtering, washing with water 15m 1 for several times, combining the washing liquid and filtrate, adding 20ml of newly prepared 2.5% ammonium chromium thiocyanate solution, stirring evenly, and standing at 10℃ for 3 hours. Filter with G4 vertical melting funnel, wash the precipitate with a small amount of ice water, drain it, dissolve the residue with acetone, transfer it to a 5ml volumetric flask, add acetone to the scale, and shake it evenly as the test solution. Take a proper amount of betaine reference substance, accurately weigh it, and add methanol hydrochloride solution (0.5→ 100) to make a solution containing 4mg per 1m 1 as reference substance solution. According to the thin-layer chromatography test (Appendix ⅵ b), 5ul of the test solution and 3μl and 6μl of the reference solution were accurately absorbed and crossed on the same silica gel G thin-layer plate. Using acetone anhydrous ethanol hydrochloric acid (10: 6: 1) as developing agent, pre-saturating for 30 minutes, developing, taking out, evaporating the solvent, and immediately spraying the newly prepared improved bismuth iodide. Scan by TLC (Appendix ⅵ b TLC scanning method), wavelength: s5 15nm, R590nm, determine the absorbance integral value of the test sample and the absorbance integral value of the reference sample, and calculate.
The content of betaine (C5H 1 1NO2) in this product shall not be less than 0.30% in terms of dry product.
14.8 Sexual taste and the sweetness of channel tropism. Enter the liver and kidney meridians.
14.9 function indications: nourishing liver and kidney, benefiting eyesight. It can be used for asthenia and asthenia, soreness of waist and knees, dizziness and tinnitus, impotence and nocturnal emission, internal heat to quench thirst, blood deficiency and sallow, and blurred vision.
14. 10 Usage and dosage 6 ~ 12g.
14. 1 1 Store in a cool and dry place to prevent sweltering heat, humidity and insects.
14. 12 from China Pharmacopoeia 20 10.
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