Yuan studied medicine from his father for nearly twenty years. Because he is steady and decisive, and good at studying medicine, he is highly valued by his father. Of the three brothers, only Yuan got his father's biography. Perhaps because of the old saying that "the waves behind the Yangtze River push the waves ahead, shine on you is better than blue", he really did not live up to his father's expectations. On the basis of inheriting Mr. Yuan Zhikui's theories, methods and prescriptions, and combining with the research results of modern cytology and immunology, he further deepened and expanded the environmental theory and put forward a more targeted and holistic theory of "three-level micro-disease environment of blood diseases" to study the internal environment of patients with blood diseases. It also reveals the development and transmission process of the four-step pathology of hematological diseases summarized by my father in patients, which makes it form a more perfect and mature theoretical system for treating hematological diseases in traditional Chinese medicine, and creates a "three-level environmental balance blood production method", which has almost reached the point of no effect in clinic.