The lipid-lowering effect (lowering LDL-C) of 5 mg rosuvastatin (Ruizhi) is equivalent to that of 10 mg atorvastatin, and the lipid-lowering effect of 10 mg rosuvastatin (Ruizhi) is equivalent to 20 mg Atorvastatin.
The recommended daily dose of rosuvastatin is 5mg~20mg, and the recommended daily dose of atorvastatin is 10mg~80mg (80mg is available in Europe and the United States, and the highest in China is 40mg).
In dosage applications, such as rosuvastatin 5mg and atorvastatin 10~20mg, the regulatory effect of these two statins on low-density lipoprotein cholesterol can reach more than 35, and if it is high When the dose is applied, the lipid-lowering intensity will further increase, and sometimes a lipid-lowering effect of more than 50% may be achieved.
Extended information:
Rosuvastatin is a selective and competitive HMG-CoA reductase inhibitor.
Atorvastatin is a selective inhibitor of HMG-CoA reductase. It reduces plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase and cholesterol biosynthesis in the liver, and It can increase the uptake and catabolism of LDL by increasing the number of low-density lipoprotein (LDL) receptors on the surface of liver cells.
This product can also reduce the production of LDL and its particle number. This product also lowers low-density lipoprotein cholesterol (LDL-C) levels in certain patients with homozygous familial hypercholesterolemia (FH) who are less likely to respond to other types of lipid-lowering drugs. answer.
Baidu Encyclopedia - Atorvastatin
Baidu Encyclopedia - Rosuvastatin Calcium Tablets