Of course it can be used, but the effect is not as good as the stone seal. For example, the seals carved on four famous stones such as Shoushan Stone and Balin Stone are clear inscriptions and have the flavor of gold and stone. They are paired with calligraphy written in ink and are endlessly interesting.
The characters on calligraphy seals are mostly written in oracle bone inscriptions, bronze inscriptions, stone drum inscriptions, and hoop inscriptions, that is, large seal script, small seal script, Chinese seal script, bird and insect script, etc. Generally, official script, regular script, imitation Song script and other fonts are not used. For regular script and official script, more neat seals can be used in seal script, while for cursive script, more extensive seals such as oracle bones and large seal scripts can be used.
If the calligraphy is long scrolls, squares, couplets, etc., generally there is no need to introduce the first chapter. If it is horizontal or vertical, you can add a first chapter in the upper right corner.