Gu Kaizhi's major is painting. He is one of the four great families in the Six Dynasties. I remember Luo Shen as his work. As a representative artist in this period, Gu Kaizhi made great contributions to the figure painting art of later generations. This paper explains the artistic characteristics of Gu Kaizhi and its influence on later generations from the perspective of Gu Kaizhi's painting practice and painting theory.