Many people say that it may be because children's immune response is stronger and more effective than that of adults, or that children have developed certain immunity after being exposed to similar viruses not long ago. But more researchers show that the difference between adults and children may be due to their vascular condition. In many adult patients with severe COVID-19's disease, there will be severe blood coagulation, which will lead to heart disease or score. Coagulation seems to be related to abnormal vascular endothelial function. Under normal circumstances, only when the body is injured and needs to stop bleeding will it form a thrombus, but if the endothelium is damaged, it may also form a thrombus. ?
Children's endothelial cells are usually better than those of adults. ? Children's endothelial cells are in a perfect state, and then deteriorate with age. ? Monagle and other medical doctors believe that children's blood vessels are better than adults' blood vessels to resist virus attacks. He said that one of the evidences supporting this view is the observation that children diagnosed in COVID-19 rarely have hypercoagulability and vascular injury. ?
In the second experiment, their team will analyze the plasma of children and adults diagnosed with COVID-19's disease, which contains protein released by damaged endothelial cells to identify potential disease markers.