Hua Tuo, Bian Que, Li Shizhen and Zhang Zhongjing all came from that dynasty.

1. Hua Tuo (about 145-208) was a famous doctor in the late Eastern Han Dynasty. Hua Tuo, Dong Feng and Zhang Zhongjing (Zhang Ji) are also called "Jian 'an Three Magical Doctors". He has a comprehensive medical skill, especially good at surgery. And proficient in internal medicine, gynecology, pediatrics, acupuncture. Hua Tuo was called "the master of surgery", "the originator of surgery" and "the doctor of Hua Tuo" by later generations.

2. Bian Que (407 BC-3 BC10) was a famous doctor in the Spring and Autumn Period and the Warring States Period. Bian Que founded the pulse diagnosis method of traditional Chinese medicine, which was the first of its kind in traditional Chinese medicine. According to legend, the famous classic of Chinese medicine "Difficult Classics" was written by Bian Que.

3. Li Shizhen (1518-1593) was a famous physician in the Ming Dynasty. After 27 years of cold and heat, Li Shizhen completed 1.590, the magnum opus Compendium of Materia Medica. In addition, there are also studies on pulse science and eight strange meridians, and there are many works, such as Textual Research on Eight Strange Meridians and Hu Ling Pulse Science. He was honored as a "medicine saint" by later generations.

4. Zhang Zhongjing (about 150-2 19), a famous doctor in the late Eastern Han Dynasty, was called a medical sage. Zhang Zhongjing extensively collected medical prescriptions and wrote the masterpiece Treatise on Febrile Diseases handed down from ancient times. The established principle of syndrome differentiation and treatment is the basic principle of TCM clinic and the soul of TCM.

Extended data:

Hua Tuo first performed surgery under general anesthesia, and was called "the originator of surgery" by later generations.

He is not only proficient in prescription science, but also admirable in acupuncture. Hua tuo visited many doctors everywhere and collected some drugs with anesthetic effect. After many different formulations of processing, he finally successfully trial-produced this anesthetic. He also mixed anesthetic with hot wine, which made the patient unconscious after taking it. Then cut open the abdominal cavity, remove the ulcer, wash away the putrefaction, sew it with mulberry thread and apply ointment, and it will be fine in one month.

So Hua Tuo gave it a name-Mafengsan.

The "Ma Fei San" he used was the earliest anesthetic in the history of the world. Hua tuo used "Ma Fei San" to perform abdominal surgery, which pioneered general anesthesia surgery. This general anesthesia operation is unprecedented in the medical history of China, and it is also a rare pioneering work in the medical history of the world.