How was the development of materia medica in Ming Dynasty? What are the two most important herbal works in Ming Dynasty?

Pharmacists in Ming Dynasty invested a lot of manpower and time in pharmaceutical research and compiled various herbal works, which greatly improved both in depth and breadth, and was an important period for the development of materia medica. There are almost more than 100 kinds of herbal works in Ming and Qing Dynasties, among which the most important ones are Liu's Compendium of Materia Medica and Li Shizhen's Compendium of Materia Medica.