The description of medical honey in China was first found in 365 kinds of medicinal materials contained in Shennong Materia Medica Classic, among which honey was listed as the top grade, and it was clearly pointed out that "honey is sweet in taste, flat in nature and non-toxic, which can restrain evil spirits in the heart, stop spasm, relieve deficiency of five internal organs, replenish qi, relieve pain and detoxify, eliminate all diseases and prolong life". Zhang Zhongjing, a medical sage, recorded the earliest suppository prescription in the world in Treatise on Febrile Diseases, which was used to treat constipation in frail patients. In the synopsis of the golden chamber, the author also introduced the treatment of "cricket abdominal pain" with licorice powder honey soup. There is a honey entry in the thirty-ninth volume of Compendium of Materia Medica by Li Shizhen, a famous pharmacist in the Ming Dynasty, which summarizes the efficacy of honey in treating diseases: "clearing heat, tonifying middle energizer, detoxifying, moistening dryness and relieving pain." . Born cold, it can clear heat; The heat is warm, so it can make up the middle; Sweet and peaceful, so you can detoxify; Soft and moist, so it can moisten dryness; Slow down and hurry up, so as to stop the pain of heart muscle sores; And therefore, it can be combined with hundreds of herbs and work together with licorice. "