2 Pharmacopoeia Standard of Ginkgo Stomach Pain Granules 2. 1 Name Ginkgo Stomach Pain Granules
Ginkgo weitong granule
2.2 Prescription of Radix Glehniae, Radix Ophiopogonis, Dendrobium, Fructus Toosendan, Rhizoma Polygonati Odorati, Radix Paeoniae Alba and Radix Glycyrrhizae Preparata.
2.3 Prepare the above seven herbs, add water and decoct them twice, the first time is 2 hours, and the second time is 1 hour. Filtering decoctions, combining filtrates, concentrating to an appropriate amount, adding 3 times of ethanol, stirring uniformly, and standing; Concentrating the supernatant to a clear paste with a relative density of1.18 ~1.22 (50℃); Take 1 part fluid extract, 2 parts sucrose and 0.8 part dextrin, and make into granules.
2.4 Characteristics This product is yellow-brown to yellow-brown granules; It tastes sweet and slightly bitter.
2.5 Identification (1) Take 25g of this product, add 30ml of petroleum ether (30 ~ 60℃), soak for 1 hour, discard the petroleum ether solution, add 50ml of ethanol, soak for 2h, pour out the supernatant, and concentrate to 1ml as the test solution. Another 65438±0g of Glycyrrhiza uralensis Fisch. was decocted twice with water, and the decoctions were combined and concentrated. To this solution, 5ml of ethanol was added and stirred to dissolve it, and the filtrate was concentrated to 0.5ml as licorice solution. According to the test of thin-layer chromatography (Appendix ⅵ b of Pharmacopoeia I, 20 10), absorb the above two solutions 15μl, and spot them on the same silica gel G thin-layer plate, using toluene-ethyl acetate-glacial acetic acid (2: 2: 0. 1) as developing agent, unfold, take out and dry. In the chromatogram of the test sample, the spots with the same color appear at the positions corresponding to the chromatogram of the control medicinal materials.
(2) Take 2g of this product, add 65438 00 ml of water, stir and dissolve, add 2.5 ml of 2 mol/L hydrochloric acid solution, heat and reflux for 30 minutes, take it out, let it cool, add 5ml of chloroform, shake and extract, separate the chloroform layer, and concentrate it to about 65438 00 ml as the test solution. In addition, take 65438±0g of Ophiopogon japonicus as reference material, add 20ml of water, decoct for 65438±00min, filter, add 2.5ml 2mol/L hydrochloric acid solution to the filtrate, and prepare the reference material solution by the same method. According to the test of thin-layer chromatography (Appendix ⅵ b of Pharmacopoeia Part I, 20 10), take 2μl of the test solution and 3μl of the control medicinal solution, respectively, and spot them on the same silica gel G thin-layer plate, with chloroform-ethyl acetate-acetone (8: 1: 1) as the developing agent, unfold, take out and dry. In the chromatogram of the test sample, the spots with the same color appear at the positions corresponding to the chromatogram of the control medicinal materials.
2.6 The inspection shall comply with the relevant provisions of Granules (Appendix I C of Pharmacopoeia 20 10).
2.7 the content was determined by high performance liquid chromatography (appendix ⅵ D of pharmacopoeia I, 20 10).
2.7. 1 chromatographic conditions and system applicability test, using octadecylsilane bonded silica gel as filler; Acetonitrile-water (15: 85) was used as the mobile phase. The detection wavelength is 230 nm. The theoretical plate number should be not less than 4000 calculated by paeoniflorin peak.
2.7.2 Preparation of reference substance solution Take a proper amount of paeoniflorin reference substance, weigh it accurately, and add methanol to make a solution containing 25μg per kloc-0/ml.
2.7.3 Preparation of test solution Take different volumes of this product, grind it, take about 2g, weigh it accurately, put it in a conical bottle with a stopper, add water 100ml accurately, plug it tightly, weigh it, perform ultrasonic treatment (power 250W, frequency 40k Hz) 10min, let it cool, and weigh it again.
2.7.4 Determination method Accurately absorb 20μl of control solution and 20μ l of test solution respectively, inject them into a liquid chromatograph, and determine to obtain the final product.
Each bag of this product contains paeoniflorin (C23H28O 1 1), not less than 8.0mg.
2.8 Indications: nourishing yin, benefiting stomach and relieving pain. It can be used for heartburn, dull pain, dry mouth, anorexia and retching caused by deficiency of stomach yin. Chronic gastritis and peptic ulcer with the above syndrome.
2.9 Usage and dosage: Take it with boiled water. 10g once, three times a day.
2. 10 specification 10g per bag.
2. 1 1 storage seal.
2. 12 Edition People's Republic of China (PRC) Pharmacopoeia 20 10 Edition
3 Ginkgo Stomach Pain Granules, the standard of Ginkgo Stomach Pain Granules by Chinese Medicine Department is 3. 1.
3.2 standard number WS3B340798
3.3 Prescription Radix Glehniae, Radix Ophiopogonis, Dendrobium, Fructus Toosendan, Rhizoma Polygonati Odorati, Radix Paeoniae Alba and Radix Glycyrrhizae (stir-fried)
3.4 Characteristics This product is yellow-brown to yellow-brown granules; It tastes sweet and slightly bitter.
3.5 Identification Take 25g of this product, add 30ml of petroleum ether (30 ~ 60℃), soak for 65438 0 hours, discard the petroleum ether solution, add 50ml of ethanol, soak for 2 hours, pour out the supernatant, and concentrate to 65438±0ml as the test solution. In addition, licorice1g. Decoct in water twice, combine decoctions, concentrate to dryness, add 5ml of ethanol, stir and dissolve, filter, and concentrate the filtrate to 0.5 ml as a reference medicinal solution. According to the thin-layer chromatography test (Appendix ⅵ b), respectively absorb the above two solutions 15μl, spot them on the same silica gel G thin-layer plate, and use ethyl toluene acetate glacial acetic acid (2:2:0. 1) as the developing agent, unfold, take them out, dry them, and immediately spray sulfuric acid solution (1→ 65433). In the chromatogram of the test sample, the spots with the same color appear at the positions corresponding to the chromatogram of the control medicinal materials.
3.6 The inspection shall comply with the relevant provisions under the item of particles (Appendix I C).
3.7 Indications: nourishing yin, benefiting stomach and relieving pain. Used for patients with burning and dull pain, dry mouth and tongue, loss of appetite, retching, chronic gastritis, peptic ulcer, etc. caused by deficiency of stomach yin.
3.8 Usage and dosage: Take it with boiling water once, 10g, three times a day.
3.9 specifications 10g per bag
3. 10 storage seal.
Drafted by Liaoning Institute for Drug Control
4 Yin Deficiency and Stomach Pain Granule Description 4. 1 Drug Type Traditional Chinese Medicine
4.2 Drug Name Yin Deficiency Stomach Pain Granule
4.3 Chinese Pinyin of Drugs 4.4 English Name of Drugs 4.5 Components 4.6 Traits 4.7 Action Category 4.8 Indications/Functions: Nourishing yin and benefiting stomach, relieving pain urgently. It can be used for heartburn, dull pain, dry mouth, anorexia and retching caused by deficiency of stomach yin. Chronic gastritis with the above symptoms.
4.9 specifications 10g per bag
4. 10 yinxu weitong granule usage and dosage: take it with boiled water. 10g once, three times a day.
4. 1 1 contraindications 4. 12 Adverse reactions 4. 13 Precautions 1. Diet should be light, avoid alcohol and spicy, cold and greasy food.
2. Avoid anger and depression and keep a good mood.
3. Deficiency cold and stomachache are not applicable.
4. Diabetic patients and those suffering from serious chronic diseases such as hypertension, heart disease, liver disease and kidney disease should be taken under the guidance of a doctor.
Children, pregnant women, lactating women and the elderly and infirm should take it under the guidance of a doctor.
6. If you have a bad stomachache, you should go to the hospital in time.
7. If the symptoms are not relieved after taking the medicine for 3 days, you should go to the hospital.
8. It is forbidden for those who are allergic to this product, and should be used with caution for those who are allergic.
9. It is forbidden to use this product when its characteristics change.
10. Children must use it under the supervision of adults.
1 1. Please keep this product out of the reach of children.
12. If you are using other drugs, please consult a doctor or pharmacist before using this product.
4. 14 drug interaction If used with other drugs, drug interaction may occur. Please consult a doctor or pharmacist for details.
4. 15 Pharmacological Effects of Yin Deficiency Stomach Pain Granules 4. 16 Remarks Please read the instructions carefully and use them according to the instructions or purchase them under the guidance of pharmacists.
Yin Deficiency Stomach Pain Granules in the ancient book Guang Yi Lun: [Volume 1] When there is a sandwich stomachache, those with both heart and stomach pains should be examined for their qi, color, spirit, pulse and tongue coating. If there is an epidemic, but the epidemic has been treated, although it is usually caused by a cold, it is nothing more. ...
Addendum to Compendium of Materia Medica: [Volume 6] Bletilla striata and White Grass Mirror: The old tree was born here. Its shape is like a tumor, and its cypress nature refers to the west, which is the gas of the west against the gold, so it can calm the stomach and treat stomachache, and also take its gas phase to protect the ears. Treat stomachache ...
Notes on Materia Medica: [Scales] Conch Conch is salty and soft. It is effective to eliminate old phlegm. Cold causes blood stasis. Duoling for stomachache. ) A clam. ...
Addendum to Compendium of Materia Medica: [Volume II Stone Department] Peach blossom salt orange garden tips: Peach blossom salt produces Wang Ze, which is as deep as peach blossom every spring, and gradually decreases in summer, white in autumn and winter, and still red in spring. Stomach pain is ruled by man, so it won't hurt if it is scalded with salt. ...
Simple meaning of medical prescription: [Volume IV Stomach Pain] Self-made Yigan Decoction