Relevant regulations on powder production and storage:
1, pulverizing raw materials should be crushed. Unless otherwise specified, oral powder should be fine powder; Powder for children and external use should be the best powder. Ophthalmic powder should be extremely fine and sterile. According to the requirements of China Pharmacopoeia, fine powder refers to the powder that can completely pass through the No.5 sieve, and the powder that can pass through the No.6 sieve is not less than 95%; The finest powder refers to the powder that can completely pass through the No.6 sieve and contains no less than 95% of the powder that can pass through the No.7 sieve; Ultrafine powder refers to the powder that can completely pass through the No.8 sieve, and the powder that can pass through the No.9 sieve is not less than 95%.
2, powder should be dry, loose, mixed evenly, consistent color. When preparing powder containing toxic drugs, precious drugs or small doses of drugs, they should be evenly mixed and sieved according to the preparation method.
3. Multi-dose packaged powder should be equipped with dose dividing devices; Oral powder containing toxic drugs should be packaged into a single dose.
4. The powder dosage may or may not contain auxiliary materials. Flavoring agent, aromatic agent, coloring agent, etc. can also be added into the oral powder. When necessary.
5. Unless otherwise specified, the powder should be stored in a sealed manner, and the powder containing volatile drugs or moisture absorption should be stored in a sealed manner. Biological products should be packed with moisture-proof materials.
6. In order to prevent gastric acid from destroying the active ingredients in the powder, auxiliary materials for neutralizing gastric acid can be selected in the powder diluent.
7. If the powder is used as a non-sterile preparation for burn treatment, it shall be marked as "non-sterile preparation" on the label; The product description should indicate that "this product is a non-sterile preparation" and clearly "it is used for mild burns (I degree or shallow II degree)" under the indications; Under the precautions, it is stipulated that "it should be used according to the doctor's advice".