Fifty-two Prescriptions for Diseases has more than 10000 words, and the book is divided into 52 questions (including 100 diseases in essence), each of which is a method to treat a disease, ranging from one or two to more than 20 prescriptions. There are 283 existing medical prescriptions, the original number should be around 300, and a few are incomplete. The names of diseases mentioned in the book are 103, including internal medicine, surgery, gynecology, pediatrics, five senses and other diseases, especially surgical diseases. Fifty-two Diseases Prescription has also made some contributions to pharmacology and prescription science. There are 247 kinds of drugs in the book, half of which are not found in Shennong Herbal Classic. In the aspect of prescription medication, the principle of syndrome differentiation and treatment was initially applied.