Contents 1 Pinyin 2 English reference 3 Overview 4 Latin name 5 English name 6 Alias ??of Xiangjiapi 7 Source 8 Plant form 9 Collection and preparation 10 Properties 11 Chemical composition 12 Nature and flavor 13 Function and indication 14 Xiangjiapi Pharmacopoeia standards 14.1 Product name 14.2 Source 14.3 Properties 14.4 Identification 14.5 Inspection 14.5.1 Moisture 14.5.2 Total ash 14.5.3 Acid-insoluble ash 14.6 Extract 14.7 Content determination 14.7.1 Chromatographic conditions and system suitability test 14.7.2 Internal standard solution Preparation 14.7.3 Determination method 14.8 Xiangjiapi decoction pieces 14.8.1 Processing 14.8.2 Identification, inspection, content determination 14.8.3 Nature, flavor and meridians 14.8.4 Function and indications 14.8.5 Usage and dosage 14.8.6 Note 14.8. 7 Storage 14.9 Source 15 References attached: 1 Prescriptions using the Chinese medicine Xiangjiapi 2 Chinese patent medicines using the Chinese medicine Xiangjiapi 3 Xiangjiapi in ancient books 1 Pinyin
xiāng jiā pí 2 English reference
periplocae cortex [Xiangya Medical Professional Dictionary]
Chinese silkvine bark [Xiangya Medical Professional Dictionary]
Cortex Periplocae (拉) [ Traditional Chinese Medicine Terminology Approval Committee. Terminology of Traditional Chinese Medicine (2004)]
Chinese silkvine rootbark [Committee for Approval of Terminology of Traditional Chinese Medicine. Terminology of Traditional Chinese Medicine (2004)]
3 Overview
Fragrance Jiapi
Xiangjiapi is a Chinese medicinal name, which is the dried root bark of Periloca sepium Bge.[1].
"The Pharmacopoeia of the People's Republic of China" (2010 edition) records the pharmacopoeia standards of this traditional Chinese medicine. 4 Latin name
Cortex Periplocae (La) ("Traditional Chinese Medicine Terminology (2004)") 5 English name
Chinese silkvine rootbark ("Traditional Chinese Medicine Terminology (2004)") 6 Fragrance Alias ??of Acanthopanax
Acanthopanax bark and Acanthopanax fragrans. 7 Source
It is the root bark of the Periloca sepium Bunge plant. 8 Plant form
A creeping shrub with latex. The leaves are opposite, membranous, lanceolate, 5-9cm long, 1.5-2.5cm wide, apex acuminate, base wedge-shaped, entire margin, with multiple pairs of lateral veins. Cymes axillary; corolla purplish red, 5 lobes, sparsely stilted inside; subcorolla ring-shaped, 5 lobes at the top, lobes filamentous, elongated, pubescent. Apophyseal fruit twins. The seeds have white silky hairs on the top. The flowering period is from June to July, and the fruiting period is from July to September.
Born in mountains, riverside, sandy texture. Mainly produced in Shanxi, Henan, Hebei and Shandong. 9 Harvesting and processing
Dig the roots in spring and autumn, take the skin and dry it in the sun. 10 Characteristics
The root bark is in the shape of a roll, and a few are irregular rolls, 2 to 4mm thick. The outer surface is grey-brown or yellow-brown, and the cork easily peels off in scales to reveal a yellow-white inner bark; the inner surface is light yellow or reddish-brown, with fine vertical lines. Crisp, uneven cross-section, light yellow. It has a special aroma and a bitter taste. 11 Chemical Ingredients
Contains ginsenosides A, B, C, D, E, F, H, H, K, 4-methoxysalicylicaldehyde, β-sitosterol, syringyl alcohol, etc. 12 Nature and flavor
Warm in nature, pungent and bitter in taste. 13 Functions and Indications
Dispel rheumatism and strengthen muscles and bones. It is used for wind-cold dampness, soreness and weakness of the waist and knees, palpitations and shortness of breath, and edema of the lower limbs. 14 Pharmacopoeia standard of Xiangjiapi 14.1 Product name
Xiangjiapi
Xiangjiapi
PERIPLOCAE CORTEX 14.2 Source
This product is Daucus lucidum The dried root bark of Periloca sepium Bge. Excavate in spring and autumn, peel off the root bark and dry in the sun.
14.3 Properties
This product is in the shape of a roll or a trough, and a few are in the shape of irregular pieces, 3 to 10cm long, 1 to 2cnl in diameter, and 0.2 to 0.4cm thick. The outer surface is grey-brown or yellow-brown, and the cork is soft and often scaly and easy to peel off. The inner surface is light yellow or light yellowish brown, relatively smooth, with fine vertical lines. It is light, brittle, easy to break, has uneven cross-section, and is yellowish white. It has a special aroma and a bitter taste. 14.4 Identification
(1) The powder of this product is light brown. The diameter of calcium oxalate square crystal is 9~20μm. The stone cells are rectangular or polygonal, with a diameter of 24 to 70 μm. The milk ducts contain colorless oil droplets. Cork cells are brown and polygonal. There are many starch grains, single grains are round or oblong, with a diameter of 3 to 11 μm; complex grains are composed of 2 to 6 grains.
(2) Take 10g of this product powder, put it in a 250ml flask, add 150ml of water, heat and distill, the distillate will have a specific aroma, collect 10ml of the distillate, put it in two test tubes, and put it in one tube. Add 1 drop of 1% ferric chloride solution, which will appear reddish brown; add 5 ml of hydrazine sulfate saturated solution and a small amount of sodium acetate crystals in another tube, heat it slightly, let it cool, and form a light yellow-green precipitate. Place a UV lamp (365nm) ), strong yellow fluorescence was observed.
(3) Take 1g of this product powder, add 10ml of ethanol, heat and reflux for 1 hour, filter, put the filtrate in a 25ml measuring bottle, add ethanol to the mark, shake well, accurately measure 1m1, and place in 20ml In the measuring bottle, add ethanol to the mark, shake well, and measure according to UV-visible spectrophotometry (Appendix V A). There is maximum absorption at the wavelength of 278nm.
(4) Take 2g of this product powder, add 30ml of methanol, heat and reflux for 1 hour, filter, evaporate the filtrate to dryness, add 2ml of methanol to the residue to dissolve, and use it as the test solution. Take another 4-methoxysalicylicaldehyde reference substance, add methanol to make a solution containing 1mg per 1ml, and use it as the reference solution. According to the thin layer chromatography (Appendix VI B) test, draw 2 μl of each of the above two solutions, place them on the same silica gel G thin layer plate, and use petroleum ether (60~90℃) ethyl acetate-glacial acetic acid (20:3 :0.5) as the developing agent, unfold, take out, dry, and spray with dinitrophenylhydrazine test solution. In the chromatogram of the test product, spots of the same color appear at the positions corresponding to the chromatogram of the reference substance. 14.5 Inspection 14.5.1 Moisture content
shall not exceed 13.0% (Appendix IXH Method 1). 14.5.2 Total ash content
shall not exceed 10.0% (Appendix IXK). 14.5.3 Acid-insoluble ash
shall not exceed 4.0% (Appendix IXK). 14.6 Leaching substance
Determine according to the hot soak method under the alcohol-soluble leachable determination method (Appendix X A), using dilute ethanol as the solvent, not less than 20.0%. 14.7 Content determination
Determination according to high performance liquid chromatography (Appendix VID). 14.7.1 Chromatographic conditions and system suitability test
Use octadecylsilane bonded silica gel as the filler; use methanol-water-acetic acid (70:30:2) as the mobile phase; the detection wavelength is 278nm. The number of theoretical plates should not be less than 1,000 based on the 4-methoxysalicylicaldehyde peak. 14.7.2 Preparation of internal standard solution
Take an appropriate amount of butyl parahydroxybenzoate, weigh it accurately, add 60% methanol to prepare a solution containing 6mg per 1ml, and you have it. 14.7.3 Determination method
Take an appropriate amount of 4-methoxysalicylicaldehyde reference substance, weigh it accurately, place it in a brown measuring bottle, add 60% methanol to prepare a solution containing 1mg per 1ml. Precisely measure 4ml of the solution and 2ml of the internal standard solution, put them into a 25ml measuring bottle, add 60% methanol to the mark, shake well, take 20μl and inject it into the liquid chromatograph, record the chromatogram; in addition, take about 0.25~0.5 of the coarse powder of this product g, dry at 60°C for 4 hours, weigh accurately, put it in a 50ml flask, add 15ml of 60% methanol, heat and reflux for 1.5 hours, filter, put the filtrate into a 25m1 measuring flask, wash the container with a small amount of 60% methanol, and filter the washing liquid In the same measuring bottle, accurately add 2 ml of internal standard solution, add 60% methanol to the mark, shake well, filter, and take the remaining filtrate as the test solution. Pipette 20 μl and inject it into the liquid chromatograph, and calculate it based on the peak area according to the internal standard method.
This product is dried at 60°C for 4 hours and contains no less than 0.20% 4-methoxysalicylicaldehyde (C8H8O3). 14.8 Xiangjiapi slices 14.8.1 Processing
Remove impurities, wash and moisten thoroughly, cut into thick slices and dry.
This product is in the form of irregular thick slices. The outer surface is gray-brown or yellow-brown, and the cork is often scaly. The inner surface is light yellow or light yellowish brown with fine vertical lines. The cut surface is yellowish white. It has a special aroma and a bitter taste. 14.8.2 Identification, inspection and content determination
Same as medicinal materials. 14.8.3 Nature, flavor and meridians
Pungent, bitter, warm; poisonous. Returns to the liver, kidney, and heart meridians. 14.8.4 Functions and indications
Diuretic, reducing swelling, dispelling rheumatism, strengthening muscles and bones.
It is used for edema of the lower limbs, palpitations and shortness of breath, wind-cold-dampness, soreness and weakness of the waist and knees. 14.8.5 Usage and dosage
3～6g. 14.8.6 Note
Do not overdose. 14.8.7 Storage
Store in a cool and dry place.
14.9 Source