2 English reference Huoxue Zhitong powder [Chinese medicine terminology examination and approval Committee. Terminology of Traditional Chinese Medicine (2004)]
Huoxue Zhitong Powder. Terminology of Traditional Chinese Medicine (2004)]
3. Information on retail guidance price of essential drugs in relevant countries of Huoxue Zhitong Powder.
Essential drug serial number
DirectoryNo. Drug name, dosage form and specification Retail unit refers to
Price category remarks 1 109 98 Huoxue Zhitong powder 1.5g bag 1 part of Chinese patent medicine *11098 Huoxue Zhitong powder 3g bag 2 part of Chinese patent medicine remarks:
1. The dosage form specifications marked with "*" in the remarks column in the table are representative products.
2. Specifications of dosage forms with "△" in the remarks column in the table, and other specifications of the same dosage form are tentative prices.
3. The dosage form specifications are indicated in the remarks column. The prices of other specifications in this dosage form are based on the same usage and dosage, and are calculated according to the drug price comparison rules.
4. The "honey pills" marked in the column of dosage form in the form include small honey pills and big honey pills.
Summarizing the name of Huoxue Zhitong Powder, there are about three prescriptions with the same name.
The main components of Chinese patent medicine Huoxue Zhitong Powder are Angelica sinensis, Notoginseng Radix, Olibanum (processed), Borneolum Syntheticum, Eupolyphaga Seu Steleophaga and Pyritum (calcined) [1]. Has the effects of promoting blood circulation, removing blood stasis, and relieving swelling and pain. Used for traumatic injury, blood stasis and swelling and pain.
Pharmacopoeia of People's Republic of China (PRC) (20 10 edition) records the pharmacopoeia standard of Huoxue Zhitong Powder.
5. Huoxue Zhitong Powder in "Prescription for Traumatology" 5. 1 was named Huoxue Zhitong Powder.
5.2 It consists of 8 parts of Angelica sinensis, 8 parts of Notopterygium root, 8 parts of Radix Angelicae Pubescentis, 8 parts of Schizonepeta tenuifolia, 8 parts of Ligusticum Chuanxiong, 8 parts of peach kernel, 3 parts of Akebia Akebia, 3 parts of Linderae, 3 parts of Dipsacus, 3 parts of Pericarpium Citri Tangerinae, 3 parts of Cortex Acanthopanacis, 3 parts of safflower, 3 parts of Saposhnikovia divaricata, 3 parts of sappan, 3 parts of frankincense, 3 parts of myrrh and 3 parts of licorice.
5.3 Efficacy: Huoxue Zhitong Powder in Dieda recipe has the function of promoting blood circulation and relieving pain.
5.4 Huoxue Zhitong Powder is used to treat traumatic injury.
5.5 Usage and dosage of Huoxue Zhitong Powder 3 yuan/serving.
5.6 The preparation method is final.
6 Huoxue Zhitong Powder was named Huoxue Zhitong Powder in Zhao Bingnan Clinical Experience Collection 6. 1.
6.2 is composed of Eupolyphaga Seu Steleophaga 10, Angelica sinensis 20, Olibanum (processed with vinegar) 4, Pyritum (processed with vinegar) 6 and Notoginseng 4.
6.3 Efficacy The Huoxue Zhitong Powder in Zhao Bingnan Clinical Experience Collection has the effects of promoting blood circulation, removing blood stasis, reducing swelling and relieving pain.
6.4 Huoxue Zhitong Powder, collected from Zhao Bingnan's clinical experience, is suitable for traumatic injury, blood stasis and swelling and pain.
6.5 Usage and dosage of Huoxue Zhitong Powder: 5 minutes each time, 1, twice a day, with warm yellow wine or warm boiled water.
6.6 The preparation method is fine powder, and the fine powder is mixed with Borneolum Syntheticum at 828 yuan 2 yuan.
7 Ancient and Modern Medicine 16 Huoxue Zhitong Powder 7. 1 Fangming Huoxue Zhitong Powder
7.2 is composed of Olibanum 1, Myrrha 1, Radix Paeoniae Rubra 1, Radix Angelicae Dahuricae 1, Rhizoma Chuanxiong 1, Radix Angelicae Sinensis 2, Radix Rehmanniae 2, Cortex Moutan 2 and Radix Glycyrrhizae 5.
7.3 Efficacy: Huoxue Zhitong Powder, Volume 16 of Guide to Ancient and Modern Medicine, has the effect of promoting blood circulation and relieving pain.
7.4 Indications: Volume XVI Huoxue Zhitong Powder in Ancient and Modern Medical Guide is mainly used for traumatic injuries, falling horses and cars, and various pains.
7.5 Usage and dosage of Huoxue Zhitong Powder: After taking 3 yuan, put warm wine into the toilet.
7.6 The preparation method is final.
8 Huoxue Zhitong Powder 8. 1 Pharmacopoeia standard named Huoxue Zhitong Powder.
Huoxue Zhitong Powder
8.2 Prescription: 400g of Angelica sinensis, 80g of Notoginseng Radix, 80g of Olibanum (prepared), 20g of Borneolum Syntheticum, 200g of Eupolyphaga Seu Steleophaga and 0/20g of native copper/kloc-.
8.3 The above six medicines, except Borneolum Syntheticum, and the other five medicines, such as Angelica sinensis, are made into the finest powder; Grinding Borneolum Syntheticum, mixing with the above powder, sieving, and mixing.
8.4 Characteristics This product is grayish brown powder; The smell is fragrant, pungent, bitter and cold.
8.5 Identification (1) Take this product, and observe it under microscope: parenchyma cells are spindle-shaped, with slightly thick walls and extremely fine oblique staggered texture (Angelica sinensis). Resin duct fragments contain yellow secretion (notoginseng). Body wall fragments are yellow or reddish brown, with round hair nests, 8 ~ 24 microns in diameter, and bristles of different lengths (Eupolyphaga sinensis) can be seen.
(2) Take about 0.65438 0 g of this product, add 65438±0ml of dilute hydrochloric acid, heat and boil for several minutes, filter, and the filtrate shows ferric salt identification reaction (Appendix IV of Pharmacopoeia I, 20 10).
(3) Take 65438+0g of this product, add 65438±05ml of petroleum ether (30 ~ 60℃), perform ultrasonic treatment for 2 ~ 3min, filter, and the filtrate volatilizes to 65438±0ml as the test solution. In addition, the borneol reference substance was added with petroleum ether (30 ~ 60℃) to prepare a solution containing 2mg per 1ml as the reference substance solution. According to the test of thin-layer chromatography (appendix ⅵ b of Pharmacopoeia I, 20 10), absorb 2μl of the above two solutions, respectively spot them on the same silica gel G thin-layer plate, and use petroleum ether (30 ~ 600℃)- ethyl acetate (19: 2) as the developing agent, unfold, take out, dry and spray 5%. In the chromatogram of the test sample, spots with the same color appear in the position corresponding to the chromatogram of the control sample.
(4) Take 6g of this product, add 40ml of ether, ultrasonic for 65438 00 minutes, filter, remove ether from the filtrate, add 2ml of ethanol to dissolve the residue, filter, and take the filtrate as the test solution. In addition, 65438 0 g of Angelica sinensis was taken as the reference substance, and 20ml of ether was added to prepare the reference substance solution by the same method. According to the test of thin-layer chromatography (Appendix ⅵ b of Pharmacopoeia I, 20 10), 2μl of each of the above two solutions was absorbed, spotted on the same silica gel G thin-layer plate, developed with n-hexane-ethyl acetate (9: 1) as developing agent, taken out, dried, and examined under ultraviolet lamp (365nm). In the chromatogram of the test sample, the fluorescent main spots with the same color are displayed at the positions corresponding to the chromatogram of the control medicinal materials.
(5) Take the standby residue under [Identification ](4) to completely volatilize the ether, add 30ml of methanol, perform ultrasonic treatment for 65438 05 minutes, filter, evaporate the filtrate, add 65438±00ml of water to dissolve the residue, shake and extract with water-saturated n-butanol twice, each time with 65438±05ml, combine n-butanol solutions, and wash with water twice. In addition, take 65438 0 g of reference substance of Panax notoginseng, add 30ml of methanol, and prepare reference substance solution by the same method. According to the test of thin-layer chromatography (Appendix ⅵ b of Pharmacopoeia I, 20 10), absorb 2μl of the above two solutions, respectively spot them on the same silica gel G thin-layer plate, use the upper solution of n-butanol-ethyl acetate-water (4: 1: 5) as the developing agent, unfold, take out, dry and spray with/kloc-0. In the chromatogram of the test sample, in the sunlight, the main spots with the same color appear at the positions corresponding to the chromatogram of the control medicinal materials; Under the ultraviolet lamp (365nm), the main fluorescent spots with the same color were observed.
8.6 The inspection shall comply with the relevant provisions under the item of powder in Appendix Ⅰ B of China Pharmacopoeia, 20 10.
8.7 The content shall be determined by high performance liquid chromatography (Appendix VI D of Pharmacopoeia I, 20 10) (dark operation).
8.7. 1 chromatographic conditions and system applicability test: octadecylsilane bonded silica gel is used as filler; The mobile phase is acetonitrile-methanol-1% acetic acid solution (1:1:5); The detection wavelength is 3 13 nm. The theoretical plate number should be not less than 2000 calculated by ferulic acid peak.
8.7.2 Preparation of reference substance solution Take a proper amount of ferulic acid reference substance, accurately weigh it, put it in a brown volumetric flask, and add methanol to make a solution containing 20μg 1ml.
8.7.3 Preparation of test solution Take about 2.3g of this product, weigh it accurately, put it in a conical flask with a stopper, add 20ml of 0.5% sodium carbonate solution, perform ultrasonic treatment (power 150w, frequency 20kHz) for 30min, centrifuge the extract (rotation speed 3000 rpm) 10min, and separate the supernatant. Every time 10ml, the human supernatant was washed with 20ml of ether saturated with 2% sodium chloride solution for 3 times, the ether solution was discarded, the pH value of the aqueous solution was adjusted to L ~ 2 with hydrochloric acid, and then extracted with ether saturated with 2% sodium chloride solution by shaking for 4 times (25ml, 25ml, 20ml, 20ml). If necessary, the emulsified layer is removed by centrifugation, and the ether extracts are combined.
8.7.4 Determination Method Accurately absorb 65,438 00μ l of control solution and test solution respectively, inject them into liquid chromatograph, and determine to obtain the product.
Every 1g of this product contains angelica, calculated by ferulic acid (C 10H 10O4), which shall not be less than 0. 10mg.
8.8 Functions and indications: promoting blood circulation to remove blood stasis, reducing swelling and relieving pain. Used for traumatic injury, blood stasis and swelling and pain.
8.9 Usage and dosage Take it with warm yellow rice wine or warm boiled water. 1.5g once and twice a day.
8. 10 Note that pregnant women are prohibited.
8. 1 1 storage seal.
8. 12 Edition People's Republic of China (PRC) Pharmacopoeia 20 10 Edition
9 Description of Huoxue Zhitong Powder 9. 1 Drug Name Huoxue Zhitong Powder
9.2 Alias of Huoxue Zhitong Powder Huoxue Zhitong Capsule
9.3 dosage form powder: 3g per bottle,1.5g; Each bag;
Capsule: 0.5g per capsule.
9.4 The main components of Huoxue Zhitong Powder are Angelica sinensis, Notoginseng Radix, Olibanum (processed), Borneolum Syntheticum, Eupolyphaga Seu Steleophaga and Pyritum (calcined). This function is:
9.5 The function of Huoxue Zhitong Powder is to promote blood circulation to remove blood stasis, reduce swelling and relieve pain. Used for traumatic injury, blood stasis and swelling and pain.
9.6 Contraindications of Huoxue Zhitong Powder 1. Pregnant women and children under 6 years old are prohibited.
2. Disabled patients with abnormal liver and kidney function.
9.7 The adverse reactions of Huoxue Zhitong Powder are unclear.
9.8 Precautions 1. Avoid cold and greasy food.
2. Children, menstrual and lactating women, the elderly and the infirm should take it under the guidance of a doctor.
3. People suffering from serious chronic diseases such as hypertension, heart disease, liver disease, diabetes and kidney disease should take it under the guidance of a doctor.
If the symptoms are not relieved after taking the medicine for 3 days, you should go to the hospital.
5. It is forbidden for those who are allergic to this product, and should be used with caution for those who are allergic.
6. It is forbidden to use this product when its characteristics change.
7. Children must use it under the supervision of adults.
8. Please keep this product out of the reach of children.
9. If you are using other drugs, please consult a doctor or pharmacist before using this product.
10. Take according to usage and dosage.
1 1. If you feel uncomfortable, you can take it with warm water.
9.9 Usage and dosage of Huoxue Zhitong Powder: Take it with warm yellow rice wine or warm boiled water. 1.5g once and twice a day.
Capsules: 2 capsules at a time, 3 times a day.
9. 10 drug interactions If used with other drugs, drug interactions may occur. Please consult a doctor or pharmacist for details.
9. 1 1 Remarks