Four difficulties refer to four kinds of pulse conditions that reflect serious diseases and syndromes in clinic. That is, the shape and qi are lost, the color and the sky are not lustrous, the pulse is solid and solid, and the pulse is against the four seasons. "The Yellow Emperor's Internal Classic, Yu Su's Collected Works": "The loss of form and qi is difficult to treat. It's hard to say that the color is dull. A strong pulse means it is very beneficial. When the pulse goes against four, there is no medicine to save it. We must examine four difficulties and make them clear. "
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