Gu Kaizhi is knowledgeable and talented. He is good at poetry, calligraphy, and especially painting. Statues of workers, Buddha statues, animals, landscapes, etc. At that time, he was known as "unparalleled in talent, painting, and crazy". His painter, Fawei, has some changes. His paintings have the characteristics of applying dyeing to the face, slightly embellishment with thick colors, and not seeking halo. The handwriting is careful and tight, like spring silkworms spinning silk and spring clouds floating in the sky. In history, Cao Buxing, Gu Kaizhi, Lu Tanwei, and Zhang Sengyao are collectively known as the "Four Great Masters of the Six Dynasties". He is proficient in painting theory, and his arguments such as "imagination is wonderful" and "describing spirit with form" have a great influence on the development of traditional Chinese painting.
Gu Kaizhi was obsessed with art and literature, and was indifferent to fame, wealth and status. He used the philosophy of life of "a mixture of infatuation and cunning, and a wise and wise person to protect oneself" to achieve the highest achievement in his art.
Gu Kaizhi and Cao Bu Xing, Lu Tanwei, and Zhang Sengyao are collectively known as the "Four Masters of the Six Dynasties". Gu Kaizhi's paintings are intended to express the spirit. His ideas such as "impressing the imagination" and "describing the spirit with form" laid the foundation for the development of traditional Chinese painting.