Here, the painter sat the Virgin Mary on her mother's lap. Although her grandmother Saint Anne is very young, she still thinks that the body of the Virgin Mary is too big for her to bear such a weight. However, the smile on Saint Anne's face is directed at his naughty little grandson-Jesus (who is breaking away from his mother and wants to ride on the lamb). Mary, like sitting in an easy chair, doesn't mind reaching out and hugging Jesus. This kind of emotional transmission is not very harmonious. Although the character processing is compact, it is not natural and vivid.
Sancta familia, a biblical theme, is the most commonly used in religious murals. Different people, painters have their own performance characteristics. Leonardo da Vinci emphasized the image of Saint Anne in this oil painting, especially her facial expression. Although his female smile formula is exposed here again, which is the highest aesthetic ideal of Leonardo da Vinci's realism, he pursues it almost like all the unknown mysteries in nature.