2. The externally applied powder for infantile diarrhea is a Chinese patent medicine, which comes from People's Republic of China (PRC) Pharmacopoeia (2000 edition) [1]. This product is a powder made of Evodia rutaecarpa, clove, white pepper, cinnamon, etc. [1]. 5g per bottle [1]. External use [1]. Make a paste with vinegar and apply it to the navel [1]. Under 2 years old, once 1/4 bottles; Under 2 years old, once 1/3 bottles [1]. If you have diarrhea more than 20 times a day, you should apply Yongquan point, and the dosage is 1/4 bottles [1]. Change the dressing every 24 hours [1]. Warming interior, dispelling cold, eliminating dampness, invigorating spleen, relieving pain and stopping diarrhea [1]. Used for abdominal pain and diarrhea caused by deficiency and cold of gastrointestinal tract and dyspepsia [1].
People's Republic of China (PRC) Pharmacopoeia (20 10 edition) records the pharmacopoeia standard of this Chinese patent medicine.
3 Pharmacopoeia Standard of Xiaoer Diarrhea External Application Powder 3. 1 Name Xiaoer Diarrhea External Application Powder
Xiaoer Fu Xie Waifu Powder
3.2 Prescription Evodia rutaecarpa, clove pepper and cinnamon
3.3 Prepare the above four ingredients, pulverize them into fine powder, sieve them, mix them evenly and pack them separately.
3.4 Properties This product is brownish yellow powder; The smell is fragrant and pungent.
3.5 Identification (1) Take this product and observe it under the microscope: the pollen grains are triangular with a diameter of about 16μm (clove). Non-glandular hair 2 ~ 6 cells, some of which are filled with reddish-brown substances; The head of glandular hair is multicellular, oval, containing brownish-yellow to brownish-red substances, and the stalk is 2 ~ 5 cells (Evodia rutaecarpa). Pericarp stone cells are round or rectangular, yellow, with a diameter of 15 ~ 40μ m and a wall thickness. Cells contain a brown substance (pepper).
(2) Take 65438+0g of this product, add 65438±00ml of ethanol, perform ultrasonic treatment for 20min, filter, and take the filtrate as the test solution. In addition, 0.5g of Evodia rutaecarpa was taken as the control medicinal material, and the control medicinal material solution was prepared by the same method. According to the test of thin-layer chromatography (Appendix ⅵ b of Pharmacopoeia Part I, 20 10), 2μl of the test solution and 2 μ l of the control medicinal solution were respectively applied to the same silica gel G thin-layer plate, and n-butanol-glacial acetic acid-water (5: 1: 1) was used as the developing agent, and then unfolded, taken out and dried. In the chromatogram of the test sample, fluorescent spots with the same color appear at the positions corresponding to the chromatogram of the control medicinal materials.
(3) Take 65438+0g of this product, add 30ml of ether, soak it for 65438+0h, shake it evenly from time to time, filter it, evaporate the filtrate, and add 65438±0ml of methanol to the residue to make it dissolve, which is used as the test solution. In addition, cinnamaldehyde reference substance was added with ethanol to prepare a solution containing 2μl per kloc-0/ml as reference substance solution. According to the test of thin-layer chromatography (Appendix ⅵ b of Pharmacopoeia I, 20 10), absorb 2μl of the above two solutions, respectively spot them on the same silica gel G thin-layer plate, and use petroleum ether (60 ~ 90℃)- ethyl acetate (17: 3) as the developing agent, unfold, take out, dry and spray dinitrophenylhydrazine ethanol. In the chromatogram of the test sample, spots with the same color appear in the position corresponding to the chromatogram of the control sample.
3.6 The inspection shall comply with the relevant provisions under the item of powder in Appendix Ⅰ B of China Pharmacopoeia, 20 10.
3.7 Indications: Warming middle warmer to dispel cold, relieving pain and stopping diarrhea. It can be used for diarrhea caused by deficiency and cold of spleen and stomach, with symptoms of loose stool, epigastric pain, and preference for warming and pressing.
3.8 Usage and dosage for external use. Paste with vinegar and apply it to navel, with children under two years old 1/4 bottles and children over two years old 1/3 bottles; For those who defecate more than 20 times a day, apply Yongquan point with a dose of 1/4 bottles and change the dressing every 24 hours.
3.9 specifications 5g per bottle
3. 10 storage seal.
3. 1 1 Edition People's Republic of China (PRC) Pharmacopoeia 20 10/Edition.
4 Instructions for External Application Powder for Infantile Diarrhea 4. 1 Drug Type Traditional Chinese Medicine
4.2 Drug Name External Application Powder for Infantile Diarrhea
4.3 Chinese Pinyin of Drugs 4.4 English Name of Drugs 4.5 Components 4.6 Traits 4.7 Category of Action 4.8 Indications/Functions: Warming middle warmer to dispel cold, relieving pain and stopping diarrhea. It can be used for diarrhea caused by deficiency and cold of spleen and stomach, with symptoms of loose stool, epigastric pain, and preference for warming and pressing.
4.9 specifications 5 grams per bottle
4. 10 external usage and dosage of Xiaoer Diarrhea External Application Powder. Paste with vinegar and apply it to navel, with children under two years old 1/4 bottles and children over two years old 1/3 bottles; For those who defecate more than 20 times a day, apply Yongquan point with a dose of 1/4 bottles and change the dressing every 24 hours.
4. 1 1 contraindications 4. 12 Adverse reactions 4. 13 Precautions 1. This product is for external use, and oral administration is prohibited.
2. Wash your hands after use, and don't touch mucous membranes such as eyes and mouth. Skin ulcers are forbidden. It is not appropriate to have a boil on the navel.
3. Avoid cold, greasy and indigestible food.
4. Babies should be used under the guidance of doctors.
5. Acute damp-heat diarrhea is not applicable.
6. Those with severe abdominal pain, diarrhea or dehydration should go to the hospital in time.
7. Patients with allergic symptoms such as rash should stop using this medicine.
8. If the symptoms are not relieved after 2 days of medication, you should go to the hospital.
9. It is forbidden for those who are allergic to this product, and should be used with caution for those who are allergic.
10. It is forbidden to use this product when its properties change.
1 1. Children must use it under the supervision of adults.
12. Please keep this product out of the reach of children.
13. If you are using other drugs, please consult a doctor or pharmacist before using this product.
4. 14 drug interaction If used with other drugs, drug interaction may occur. Please consult a doctor or pharmacist for details.
4. 15 Pharmacological Effects of Xiaoer Diarrhea External Application Powder 4. 16 Remarks